There are 10 ways to get from Gainesville to Portsmouth by bus, plane, train, bus (Flixbus, Greyhound), car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Jacksonville, fly to Boston Logan Airport, bus
best- Take the bus from Gainesville to Jacksonvillebus
- Fly from Jacksonville (JAX) to Boston Logan Airport (BOS)plane JAX - BOS
- Take the bus from Boston to Portsmouthbus
9h 24m$126–547Drive to Orlando Sanford, fly to Portsmouth International Airport At Pease
cheapest- Drive from Gainesville to Orlando-Sanford-Airport-SFBcar
- Fly from Orlando Sanford (SFB) to Portsmouth International Airport At Pease (PSM)plane SFB - PSM
8h$122–521Bus, train
- Take the bus from Gainesville to Jacksonvillebus
- Take the train from Jacksonville to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain
- Take the bus from Boston to Portsmouth Bus Stopbus
28h 28m$389–837Bus
- Take the bus from Gainesville to Jacksonvillebus
- Take the bus from Jacksonville to New York City Chinatownbus
- Take the bus from NYC Downtown to Bostonbus
- Take the bus from Boston to Portsmouth Bus Stopbus
29h 9m$198–339Drive 1,249.1 mi
- Drive from Gainesville to Portsmouthcar 1,249.1 mi
21h 57m$228–330Bus to Orlando, fly to Boston Logan Airport, bus
- Take the bus from University of Florida - 1956 Gale Lemerand Dr to Orlando - RedCoach Station, FLbus
- Fly from Orlando (MCO) to Boston Logan Airport (BOS)plane MCO - BOS
- Take the bus from Boston to Portsmouthbus
9h 13m$196–784Fly Gainesville Regional Airport to Manchester Airport, bus
- Fly from Gainesville Regional Airport (GNV) to Manchester Airport (MHT)plane GNV - MHT
- Take the bus from Boston Manchester Airport to Bostonbus
- Take the bus from Boston to Portsmouth Bus Stopbus
10h 51m$126–584Bus to Orlando, fly to Manchester Airport, bus
- Take the bus from University of Florida - 1956 Gale Lemerand Dr to Orlando - RedCoach Station, FLbus
- Fly from Orlando (MCO) to Manchester Airport (MHT)plane MCO - MHT
- Take the bus from Boston Manchester Airport to Bostonbus
- Take the bus from Boston to Portsmouth Bus Stopbus
10h 45m$246–689Bus to Orlando, fly to Theodore Francis Green State Airport, train, bus
- Take the bus from University of Florida - 1956 Gale Lemerand Dr to Orlando - RedCoach Station, FLbus
- Fly from Orlando (MCO) to Theodore Francis Green State Airport (PVD)plane MCO - PVD
- Take the train from TF Green Airport to South Stationtrain
- Take the bus from Boston to Portsmouth Bus Stopbus
10h 46m$188–480Bus via Atlanta
- Take the bus from Gainesville Bus Stop to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Port Authority Bus Terminalbus
- Take the bus from Port Authority Bus Terminal to Bostonbus
- Take the bus from Boston to Portsmouthbus
38h 25m$238–460
Gainesville to Portsmouth by bus and train
Questions & Answers
The cheapest way to get from Gainesville to Portsmouth is to bus which costs $190 - $340 and takes 29h 9m.
The fastest way to get from Gainesville to Portsmouth is to drive and fly which takes 8h and costs $120 - $550.
No, there is no direct bus from Gainesville to Portsmouth. However, there are services departing from Gainesville and arriving at Portsmouth Bus Stop via Jacksonville, NYC Downtown and Boston. The journey, including transfers, takes approximately 29h 9m.
The distance between Gainesville and Portsmouth is 1160 miles. The road distance is 1256.4 miles.
The best way to get from Gainesville to Portsmouth without a car is to bus and train which takes 28h 28m and costs $380 - $850.
It takes approximately 9h 24m to get from Gainesville to Portsmouth, including transfers.
Gainesville to Portsmouth bus services, operated by Flixbus USA, depart from Gainesville station.
Gainesville to Portsmouth bus services, operated by Flixbus USA, arrive at Jacksonville station.
Yes, the driving distance between Gainesville to Portsmouth is 1256 miles. It takes approximately 21h 57m to drive from Gainesville to Portsmouth.
Book your Gainesville to Portsmouth bus tickets online with Omio and FlixBus.
What companies run services between Gainesville, FL, USA and Portsmouth, NH, USA?
You can take a bus from Gainesville to Portsmouth Bus Stop via Jacksonville, New York City Chinatown, NYC Downtown, and Boston in around 29h 9m.
- Website
- southwest.com
Flights from Jacksonville to Boston Logan Airport via Baltimore
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $100–500
Flights from Orlando to Boston Logan Airport via Baltimore
- Ave. Duration
- 4h 41m
- When
- Monday, Thursday, Friday, Tuesday, Wednesday, and Sunday
- Estimated price
- $90–430
Flights from Orlando to Manchester Airport
- Ave. Duration
- 2h 56m
- When
- Every day
- Estimated price
- $100–470
Flights from Orlando to Manchester Airport via Baltimore
- Ave. Duration
- 5h 6m
- When
- Tuesday, Wednesday, Sunday, Monday, Thursday, and Friday
- Estimated price
- $100–480
Flights from Orlando to Theodore Francis Green State Airport
- Ave. Duration
- 2h 45m
- When
- Every day
- Estimated price
- $65–320
Flights from Orlando to Theodore Francis Green State Airport via Baltimore
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $65–320
- Website
- jetblue.com
Flights from Jacksonville to Boston Logan Airport
- Ave. Duration
- 2h 41m
- When
- Every day
- Estimated price
- $100–500
Flights from Orlando to Boston Logan Airport
- Ave. Duration
- 3h 6m
- When
- Every day
- Estimated price
- $90–430
Flights from Orlando to Theodore Francis Green State Airport
- Ave. Duration
- 2h 56m
- When
- Every day
- Estimated price
- $65–320
- Website
- aa.com
Flights from Orlando to Boston Logan Airport
- Ave. Duration
- 3h 8m
- When
- Every day
- Estimated price
- $90–430
Flights from Gainesville Regional Airport to Manchester Airport via Charlotte
- Ave. Duration
- 6h 47m
- When
- Every day
- Estimated price
- $110–550
Flights from Gainesville Regional Airport to Manchester Airport via Miami, Reagan Washington
- Ave. Duration
- 10h 23m
- When
- Every day
- Estimated price
- $140–650
Flights from Orlando to Manchester Airport via Reagan Washington
- Ave. Duration
- 5h 28m
- When
- Every day
- Estimated price
- $100–480
Flights from Orlando to Manchester Airport via Philadelphia
- Ave. Duration
- 5h 58m
- When
- Every day
- Estimated price
- $100–480
- Website
- delta.com
Flights from Jacksonville to Boston Logan Airport
- Ave. Duration
- 2h 51m
- When
- Every day
- Estimated price
- $100–500
Flights from Orlando to Boston Logan Airport
- Ave. Duration
- 3h 12m
- When
- Every day
- Estimated price
- $90–430
- Website
- united.com
Flights from Jacksonville to Boston Logan Airport via Washington Dulles
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $100–550
Flights from Orlando to Manchester Airport via Washington Dulles
- Ave. Duration
- 5h 41m
- When
- Every day
- Estimated price
- $100–480
- Website
- flybreeze.com
Flights from Orlando to Manchester Airport via Raleigh/Durham
- Ave. Duration
- 4h 45m
- When
- Thursday and Sunday
- Estimated price
- $200–600
Flights from Orlando to Manchester Airport via Charleston
- Ave. Duration
- 5h 39m
- When
- Wednesday and Saturday
- Estimated price
- $200–600
Flights from Orlando to Theodore Francis Green State Airport
- Ave. Duration
- 2h 57m
- When
- Every day
- Estimated price
- $140–390
Flights from Orlando to Theodore Francis Green State Airport via Myrtle Beach
- Ave. Duration
- 5h 38m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- $140–390
- Website
- flyfrontier.com
Flights from Orlando to Boston Logan Airport
- Ave. Duration
- 3h 9m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $140–430
- Website
- allegiantair.com
Flights from Orlando Sanford to Portsmouth International Airport At Pease
- Ave. Duration
- 2h 54m
- When
- Thursday and Sunday
- Estimated price
- $100–490
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Jacksonville to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 18h 39m
- Frequency
- Once daily
- Estimated price
- $300–650
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 4h 21m
- Frequency
- Every 3 hours
- Estimated price
- $70–150
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 3h 47m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $50–490
- First Class
- $200–750
Train from TF Green Airport to South Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $9–16
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $9–16
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Gainesville to Jacksonville
- Ave. Duration
- 1h 30m
- Frequency
- 4 times a week
- Estimated price
- $10–17
- Schedules at
- Flixbus USA
Bus from Gainesville to Jacksonville
- Ave. Duration
- 1h 30m
- Frequency
- 4 times a week
- Estimated price
- $10–17
- Schedules at
- Flixbus USA
Bus from Boston to Portsmouth Bus Stop
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- $8–15
- Schedules at
- Flixbus USA
Bus from Gainesville to Jacksonville
- Ave. Duration
- 1h 30m
- Frequency
- 4 times a week
- Estimated price
- $10–17
- Schedules at
- Flixbus USA
Bus from Jacksonville to New York City Chinatown
- Ave. Duration
- 18h 35m
- Frequency
- 5 times a week
- Estimated price
- $150–250
- Schedules at
- Flixbus USA
Bus from NYC Downtown to Boston
- Ave. Duration
- 5h
- Frequency
- Every 4 hours
- Estimated price
- $30–55
- Schedules at
- Flixbus USA
Bus from Boston to Portsmouth Bus Stop
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- $8–15
- Schedules at
- Flixbus USA
Bus from Boston to Portsmouth Bus Stop
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- $8–15
- Schedules at
- Flixbus USA
Bus from Boston to Portsmouth Bus Stop
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- $8–15
- Schedules at
- Flixbus USA
Bus from Boston to Portsmouth Bus Stop
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- $8–15
- Schedules at
- Flixbus USA
- Phone
- +1 603-430-1100
- Website
- C & J Travel
Bus from Boston to Portsmouth
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $15–27
- Website
- C & J Travel
Bus from Boston to Portsmouth
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $15–27
- Website
- C & J Travel
Bus from Boston to Portsmouth
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $15–27
- Website
- C & J Travel
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Boston to Portsmouth Bus Stop
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $8–17
- Website
- Greyhound
Bus from Boston to Portsmouth Bus Stop
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $8–17
- Website
- Greyhound
Bus from Boston Manchester Airport to Boston
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- $7–15
- Website
- Greyhound
Bus from Boston to Portsmouth Bus Stop
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $8–17
- Website
- Greyhound
Bus from Boston Manchester Airport to Boston
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- $7–15
- Website
- Greyhound
Bus from Boston to Portsmouth Bus Stop
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $8–17
- Website
- Greyhound
Bus from Boston to Portsmouth Bus Stop
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $8–17
- Website
- Greyhound
Bus from Gainesville Bus Stop to Atlanta Bus Station
- Ave. Duration
- 7h 25m
- Frequency
- Once daily
- Estimated price
- $50–95
- Website
- Greyhound
Bus from Atlanta Bus Station to Port Authority Bus Terminal
- Ave. Duration
- 19h 15m
- Frequency
- 4 times a day
- Estimated price
- $140–270
- Website
- Greyhound
Bus from Port Authority Bus Terminal to Boston
- Ave. Duration
- 5h 4m
- Frequency
- Hourly
- Estimated price
- $30–65
- Website
- Greyhound
- Phone
- +1 877 733 0724
- Website
- RedCoach
Bus from University of Florida - 1956 Gale Lemerand Dr to Orlando - RedCoach Station, FL
- Ave. Duration
- 2h
- Frequency
- 4 times a day
- Estimated price
- $29–55
- Website
- RedCoach
Bus from University of Florida - 1956 Gale Lemerand Dr to Orlando - RedCoach Station, FL
- Ave. Duration
- 2h
- Frequency
- 4 times a day
- Estimated price
- $29–55
- Website
- RedCoach
Bus from University of Florida - 1956 Gale Lemerand Dr to Orlando - RedCoach Station, FL
- Ave. Duration
- 2h
- Frequency
- 4 times a day
- Estimated price
- $29–55
- Website
- RedCoach
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