There are 3 ways to get from Gainesville to San Antonio by bus (Flixbus), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Flixbus)
best- Take the bus from Gainesville to University of South Floridabus FlixBus N2467
2h 34m$83–110Drive 101.7 mi
cheapest- Drive from Gainesville to San Antoniocar 101.7 mi
1h 46m$19–27Bus via Wiregrass Park n Ride
- Take the bus from University of Florida - 1956 Gale Lemerand Dr to University of South Florida - 3801 USF Holly Drbus Tallahassee
4h 33m$65–106
Questions & Answers
The cheapest way to get from Gainesville to San Antonio is to drive which costs $18 - $27 and takes 1h 46m.
The fastest way to get from Gainesville to San Antonio is to drive which takes 1h 46m and costs $18 - $27.
No, there is no direct bus from Gainesville to San Antonio. However, there are services departing from Gainesville and arriving at University of South Florida via . The journey, including transfers, takes approximately 2h 34m.
The distance between Gainesville and San Antonio is 147 miles. The road distance is 102.3 miles.
The best way to get from Gainesville to San Antonio without a car is to bus which takes 2h 34m and costs $80 - $110.
It takes approximately 2h 34m to get from Gainesville to San Antonio, including transfers.
Gainesville to San Antonio bus services, operated by Flixbus USA, depart from Gainesville station.
Gainesville to San Antonio bus services, operated by Flixbus USA, arrive at University of South Florida station.
Yes, the driving distance between Gainesville to San Antonio is 102 miles. It takes approximately 1h 46m to drive from Gainesville to San Antonio.
There are 97+ hotels available in San Antonio.
What companies run services between Gainesville, FL, USA and San Antonio, FL, USA?
Flixbus USA operates a bus from Gainesville to University of South Florida once daily. Tickets cost $18–30 and the journey takes 2h 5m.
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Gainesville to University of South Florida
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $18–30
- Schedules at
- Flixbus USA
- Phone
- +1 877 733 0724
- Website
- RedCoach
Bus from University of Florida - 1956 Gale Lemerand Dr to University of South Florida - 3801 USF Holly Dr
- Ave. Duration
- 2h 40m
- Frequency
- Once daily
- Estimated price
- $30–60
- Website
- RedCoach
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide





