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How to get fromGainesville to Sanibel Islandby bus, car, plane, or bus (Flixbus)

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There are 6 ways to get from Gainesville to Sanibel Island by bus, car, plane, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from University of Florida - 1956 Gale Lemerand Dr to Fort Myers 7-11bus bus Tallahassee
    5h 50m
    $133–206

  2. Drive 248.1 mi

    cheapest
    1. Drive from Gainesville to Sanibel Islandcar car 248.1 mi
    5h 7m
    $46–66

  3. Fly Gainesville Regional Airport to Ft. Myers

    1. Fly from Gainesville Regional Airport (GNV) to Ft. Myers (RSW)plane plane GNV - RSW
    5h 45m
    $166–542

  4. Bus via University

    1. Take the bus from Gainesville to University of South Floridabus bus FlixBus N2467
    2. Take the bus from University of South Florida - 3801 USF Holly Dr to Fort Myers 7-11bus bus Tallahassee
    6h 15m
    $120–188

  5. Bus to Orlando, fly to Ft. Myers

    1. Take the bus from University of Florida - 1956 Gale Lemerand Dr to Orlando - RedCoach Station, FLbus bus
    2. Fly from Orlando (MCO) to Ft. Myers (RSW)plane plane MCO - RSW
    5h
    $396–745

  6. Fly Gainesville Regional Airport to Miami International Airport, bus

    1. Fly from Gainesville Regional Airport (GNV) to Miami International Airport (MIA)plane plane GNV - MIA
    2. Take the bus from Miami Airport to Fort Myers 7-11bus bus
    6h 59m
    $156–472

Gainesville Regional Airport (GNV) to Ft. Myers (RSW) flights

Calendar62Weekly Planes
Duration6h 3mAverage Duration
Ticket$91Cheapest Price
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Questions & Answers

Map of how to get from Gainesville to Sanibel Island.ExpandLaunch map view
  • Distance: 278.8 mi
  • Duration: 5h 50m

What companies run services between Gainesville, FL, USA and Sanibel Island, FL, USA?

RedCoach operates a bus from University of Florida - 1956 Gale Lemerand Dr to Fort Myers 7-11 once daily. Tickets cost $60–120 and the journey takes 5h 15m. Alternatively, Delta and American Airlines fly from Gainesville Regional Airport (GNV) to Ft. Myers (RSW) every 3 hours.

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