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How to get fromGaithersburg to Florenceby train (Amtrak), bus (Greyhound, Flixbus), car, plane, bus, train, or subway

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There are 7 ways to get from Gaithersburg to Florence by train (Amtrak), bus (Greyhound, Flixbus), car, plane, bus, train, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Washington Union Station to Florence Stationtrain train Palmetto / ...
    9h 26m
    $102–243

  2. Bus

    cheapest
    1. Take the bus from Washington Union Station to Raleigh Bus Stationbus bus Greyhound US0670 / ...
    2. Take the bus from Raleigh Bus Station to Florence Bus Stationbus bus Greyhound US0642S / ...
    10h 49m
    $63–112

  3. Drive  416.7 mi

    1. Drive from Gaithersburg to Florencecar car 416.7 mi
    7h 4m
    $76–110

  4. Fly from Ronald Reagan Washington National Airport, bus

    1. Fly from Ronald Reagan Washington National Airport (DCA) to Myrtle Beach (MYR)plane plane DCA - MYR
    2. Take the bus from Myrtle Beach Bus Station to Florence Bus Stationbus bus
    6h 6m
    $95–508

  5. Bus, train

    1. Take the bus from Washington Union Station to Fayetteville Bus Stationbus bus FlixBus N2471 / ...
    2. Take the train from Fayetteville Amtrak Station to Florence Stationtrain train Palmetto / ...
    11h 13m
    $69–132

  6. Bus to Baltimore-Washington International Airport, fly, bus

    1. Take the bus from Gaithersburg Park & Ride to BWI SOUTHWEST AIRLINES eb UPPER LEVELbus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Myrtle Beach (MYR)plane plane BWI - MYR
    3. Take the bus from Myrtle Beach Bus Station to Florence Bus Stationbus bus
    6h 32m
    $323–683

  7. Subway to Washington Dulles International Airport, fly, bus

    1. Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    2. Fly from Washington Dulles International Airport (IAD) to Myrtle Beach (MYR)plane plane IAD - MYR
    3. Take the bus from Myrtle Beach Bus Station to Florence Bus Stationbus bus
    9h 5m
    $75–367

Gaithersburg to Florence by subway and train (Amtrak)

Calendar14Weekly Services
Duration9h 26mAverage Duration
Ticket$102Cheapest Price
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Comparing Your Travel Options

Map of how to get from Gaithersburg to Florence.ExpandLaunch map view
  • Distance: 426.8 mi
  • Duration: 9h 26m

What companies run services between Gaithersburg, MD, USA and Florence, SC, USA?

Amtrak operates a train from Washington Union Station to Florence Station twice daily. Tickets cost $100–240 and the journey takes 7h 48m. Alternatively, you can take a bus from S Frederick Ave & Summit Ave to Florence Bus Station via Medical Center Station & Bay E, Medical Center, Red Line Center Platform, Union Station, Red Line Center Platform, Washington Union Station, and Raleigh Bus Station in around 10h 49m.

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