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How to get fromGaithersburg to Knoxvilleby bus, plane, train, car, subway, or bus (Flixbus)

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There are 10 ways to get from Gaithersburg to Knoxville by bus, plane, train, car, subway, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Baltimore-Washington International Airport, fly to Mcghee Tyson Airport

    best
    1. Take the bus from Gaithersburg Park & Ride to BWI SOUTHWEST AIRLINES eb UPPER LEVELbus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Mcghee Tyson Airport (TYS)plane plane BWI - TYS
    4h 13m
    $237–1,172

  2. Drive  483.9 mi

    cheapest
    1. Drive from Gaithersburg to Knoxvillecar car 483.9 mi
    8h 26m
    $89–128

  3. Train, bus

    1. Take the train from Washington Union Station to Ny Moynihan Train Hall At Penn Stationtrain train Acela
    2. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    17h 34m
    $260–356

  4. Subway to Ronald Reagan Washington National Airport, fly to Mcghee Tyson Airport

    1. Take the subway from Shady Grove, Red Line Center Platform to Gallery Place, Red Line Track 1 Platformsubway subway
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Mcghee Tyson Airport (TYS)plane plane DCA - TYS
    3h 58m
    $279–1,477

  5. Subway to Washington Dulles International Airport, fly to Mcghee Tyson Airport

    1. Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    2. Fly from Washington Dulles International Airport (IAD) to Mcghee Tyson Airport (TYS)plane plane IAD - TYS
    4h 15m
    $199–976

  6. Fly Ronald Reagan Washington National Airport to Chattanooga Metropolitan Airport, drive

    1. Fly from Ronald Reagan Washington National Airport (DCA) to Chattanooga Metropolitan Airport (CHA)plane plane DCA - CHA
    2. Drive from Chattanooga Metropolitan Airport (CHA) to Knoxvillecar car
    5h 42m
    $117–635

  7. Fly Ronald Reagan Washington National Airport to Asheville Regional Airport, drive

    1. Fly from Ronald Reagan Washington National Airport (DCA) to Asheville Regional Airport (AVL)plane plane DCA - AVL
    2. Drive from Asheville-Airport-AVL to Knoxvillecar car
    5h 43m
    $111–592

  8. Bus

    1. Take the bus from Bethesda, MD to Penn Station 7th Ave. Corner of W 30th Streetbus bus Lorton
    2. Take the bus from New York to Knoxvillebus bus Nyc
    19h 36m
    $238–355

  9. Bus via Baltimore

    1. Take the bus from Gaithersburg Park & Ride to Warner Stbus bus 201
    2. Take the bus from Baltimore to New Yorkbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    20h 5m
    $230–340

  10. Bus #2

    1. Take the bus from Washington Union Station to New York City Chinatownbus bus FlixBus N2471 / ...
    2. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    23h 35m
    $143–187

Baltimore-Washington International Airport (BWI) to Mcghee Tyson Airport (TYS) flights

Calendar41Weekly Planes
Duration3h 7mAverage Duration
Ticket$182Cheapest Price
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Comparing Your Travel Options

Map of how to get from Gaithersburg to Knoxville.ExpandLaunch map view
  • Distance: 521.1 mi
  • Duration: 4h 13m

What companies run services between Gaithersburg, MD, USA and Knoxville, TN, USA?

You can take a bus from S Frederick Ave & Summit Ave to Knoxville via Medical Center Station & Bay E, Rockville Pk+South Dr, Montgomery Av+Waverly St, Bethesda, MD, Penn Station 7th Ave. Corner of W 30th Street, 23 St, East Broadway, New York, and Knoxville in around 19h 36m.

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