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How to get fromGaithersburg to St. Louisby plane, bus (Greyhound), train (Amtrak), car, bus, subway, or train

Find Transport to St. Louis

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There are 7 ways to get from Gaithersburg to St. Louis by plane, bus (Greyhound), train (Amtrak), car, bus, subway, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Ronald Reagan Washington National Airport

    best
    1. Fly from Ronald Reagan Washington National Airport (DCA) to Lambert–St. Louis International Airport (STL)plane plane DCA - STL
    5h 1m
    $137–440

  2. Subway to Washington Dulles International Airport, fly

    cheapest
    1. Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    2. Fly from Washington Dulles International Airport (IAD) to Lambert–St. Louis International Airport (STL)plane plane IAD - STL
    5h 45m
    $107–609

  3. Bus

    1. Take the bus from SHADY GROVE & station to Frederick Marc Stationbus bus 515
    2. Take the bus from Frederick Bus Station to Pittsburgh Intermodal Stationbus bus
    3. Take the bus from Pittsburgh Intermodal Station to St Louis Bus Stationbus bus
    21h 20m
    $134–226

  4. Train (Amtrak)

    1. Take the train from Rockville Amtrak to Chicago Union Stationtrain train Floridian
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    24h 14m
    $562–892

  5. Drive  781.8 mi

    1. Drive from Gaithersburg to St. Louiscar car 781.8 mi
    13h 34m
    $143–207

  6. Bus to Baltimore-Washington International Airport, fly

    1. Take the bus from Gaithersburg Park & Ride to BWI SOUTHWEST AIRLINES eb UPPER LEVELbus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Lambert–St. Louis International Airport (STL)plane plane BWI - STL
    5h 19m
    $125–705

  7. Train, bus

    1. Take the train from Rockville Amtrak to Pittsburgh Amtrak Stationtrain train Floridian
    2. Take the bus from Pittsburgh Intermodal Station to St Louis Bus Stationbus bus Greyhound US0421
    22h 59m
    $252–414

Gaithersburg to St. Louis by bus

Calendar10Weekly Buses
Duration21h 20mAverage Duration
Ticket$134Cheapest Price
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Comparing Your Travel Options

Map of how to get from Gaithersburg to St. Louis.ExpandLaunch map view
  • Distance: 754.3 mi
  • Duration: 5h 1m

What companies run services between Gaithersburg, MD, USA and St. Louis, MO, USA?

American Airlines and Southwest Airlines fly from Ronald Reagan Washington National Airport (DCA) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, you can take a bus from N Frederick Ave & Brookes Ave to St Louis Bus Station via Shady Grove Station & Bay L, SHADY GROVE & station, Frederick Bus Station, and Pittsburgh Intermodal Station in around 21h 20m.

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