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How to get fromGalena to Indianapolisby bus (Flixbus), bus, train, car, plane, or bus (Greyhound)

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There are 8 ways to get from Galena to Indianapolis by bus (Flixbus), bus, train, car, plane, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Dubuque to Madisonbus bus Lab 121
    2. Take the bus from Madison to Indianapolisbus bus FlixBus 2514
    11h 15m
    $135–180

  2. Drive  341.8 mi

    cheapest
    1. Drive from Galena to Indianapoliscar car 341.8 mi
    6h 11m
    $59–85

  3. Bus, train via Milwaukee

    1. Take the bus from Dubuque to Milwaukeebus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Indianapolistrain train
    13h 18m
    $242–359

  4. Drive to Quad City International Airport, fly

    1. Drive from Galena to Moline-Airport-MLIcar car
    2. Fly from Quad City International Airport (MLI) to Indianapolis (IND)plane plane MLI - IND
    6h 48m
    $87–494

  5. Bus via Chicago

    1. Take the bus from Dubuque to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Bus Station to Indianapolis Union Stationbus bus
    11h 48m
    $141–210

  6. Bus, train

    1. Take the bus from Dubuque to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the train from Chicago Union Station to Indianapolistrain train
    13h 30m
    $211–330

  7. Bus, train via Madison

    1. Take the bus from Dubuque to Madisonbus bus
    2. Take the bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrakbus bus
    3. Take the train from Milwaukee to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to Indianapolistrain train
    13h 58m
    $249–385

  8. Bus to Dane County Regional Airport-Truax Field, fly

    1. Take the bus from Dubuque to Madisonbus bus
    2. Fly from Dane County Regional Airport-Truax Field (MSN) to Indianapolis (IND)plane plane MSN - IND
    9h 31m
    $159–564

Quad City International Airport (MLI) to Indianapolis (IND) flights

Calendar76Weekly Planes
Duration5h 18mAverage Duration
Ticket$72Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Galena to Indianapolis.ExpandLaunch map view
  • Distance: 448.5 mi
  • Duration: 11h 15m

What companies run services between Galena, IL, USA and Indianapolis, IN, USA?

You can take a vehicle from Galena to Indianapolis via Dubuque and Madison in around 11h 15m.

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