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How to get fromGalena to Louisvilleby car, plane, bus (Flixbus, Greyhound, Amtrak), bus, bus (Amtrak), or train

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There are 8 ways to get from Galena to Louisville by car, plane, bus (Flixbus, Greyhound, Amtrak), bus, bus (Amtrak), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Quad City International Airport, fly

    best
    1. Drive from Galena to Moline-Airport-MLIcar car
    2. Fly from Quad City International Airport (MLI) to Louisville International Airport (SDF)plane plane MLI - SDF
    7h 12m
    $112–626

  2. Drive  456.5 mi

    cheapest
    1. Drive from Galena to Louisvillecar car 456.5 mi
    8h 3m
    $84–121

  3. Bus via Indianapolis

    1. Take the bus from Dubuque to Madisonbus bus
    2. Take the bus from Madison to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Indianapolis Union Stationbus bus
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    15h 10m
    $161–240

  4. Bus to Dane County Regional Airport-Truax Field, fly

    1. Take the bus from Dubuque to Madisonbus bus
    2. Fly from Dane County Regional Airport-Truax Field (MSN) to Louisville International Airport (SDF)plane plane MSN - SDF
    10h 8m
    $178–705

  5. Bus, bus to Chicago O'Hare International Airport, fly

    1. Take the bus from Dubuque to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus bus
    3. Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane plane ORD - SDF
    10h 18m
    $179–613

  6. Bus

    1. Take the bus from Dubuque to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Union Station to Louisville, KYbus bus
    15h 21m
    $161–220

  7. Bus, train

    1. Take the bus from Dubuque to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the train from Chicago Union Station to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    16h 25m
    $233–375

  8. Bus, train via Milwaukee

    1. Take the bus from Dubuque to Madisonbus bus
    2. Take the bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrakbus bus
    3. Take the train from Milwaukee to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to Indianapolistrain train
    5. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    16h 53m
    $271–430

Quad City International Airport (MLI) to Louisville International Airport (SDF) flights

Calendar80Weekly Planes
Duration5h 13mAverage Duration
Ticket$96Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Galena to Louisville.ExpandLaunch map view
  • Distance: 433.1 mi
  • Duration: 7h 12m

What companies run services between Galena, IL, USA and Louisville, KY, USA?

You can take a vehicle from Galena to Louisville, KY via Dubuque, Madison, Chicago Bus Station, and Indianapolis Union Station in around 15h 10m.

Airlines
Train operators
Bus operators

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