There are 8 ways to get from Galena to Louisville by car, plane, bus, train, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Quad City International Airport, fly
best- Drive from Galena to Moline-Airport-MLIcar
- Fly from Quad City International Airport (MLI) to Louisville International Airport (SDF)plane MLI - SDF
6h 52m$93–488Drive 456.5 mi
cheapest- Drive from Galena to Louisvillecar 456.5 mi
8h 2m$84–121Bus
- Take the bus from Dubuque to Madisonbus
- Take the bus from Madison to Indianapolisbus
- Take the bus from Indianapolis to Louisville Bus Stationbus
14h 2m$198–278Bus, train via Milwaukee
- Take the bus from Dubuque to Madisonbus
- Take the bus from UW Madison Campus - N Lake St to Milwaukee Intermodalbus
- Take the train from Milwaukee to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Indianapolistrain
- Take the bus from Indianapolis Union Station to Louisville Bus Stationbus
16h 29m$204–373Bus to Dane County Regional Airport-Truax Field, fly
- Take the bus from Dubuque to Madisonbus
- Fly from Dane County Regional Airport-Truax Field (MSN) to Louisville International Airport (SDF)plane MSN - SDF
9h 43m$186–713Bus, bus to Chicago O'Hare International Airport, fly
- Take the bus from Dubuque to Madisonbus
- Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane ORD - SDF
10h$172–571Bus via Chicago
- Take the bus from Dubuque to Madisonbus
- Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus
- Take the bus from Chicago Bus Station to Louisville Bus Stationbus
14h 41m$154–258Bus, train
- Take the bus from Dubuque to Madisonbus
- Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus
- Take the train from Chicago Union Station to Indianapolistrain
- Take the bus from Indianapolis Union Station to Louisville Bus Stationbus
16h 3m$191–348
Quad City International Airport (MLI) to Louisville International Airport (SDF) flights
Questions & Answers
The cheapest way to get from Galena to Louisville is to drive which costs $80 - $120 and takes 8h 2m.
The fastest way to get from Galena to Louisville is to drive and fly which takes 6h 52m and costs $90 - $490.
No, there is no direct bus from Galena to Louisville station. However, there are services departing from Dubuque and arriving at Louisville Bus Station via Madison and Indianapolis. The journey, including transfers, takes approximately 14h 2m.
The distance between Galena and Louisville is 440 miles. The road distance is 459.2 miles.
The best way to get from Galena to Louisville without a car is to bus which takes 14h 2m and costs $190 - $280.
It takes approximately 6h 52m to get from Galena to Louisville, including transfers.
Galena to Louisville bus services, operated by Jefferson Lines, depart from Dubuque station.
Galena to Louisville bus services, operated by Jefferson Lines, arrive at Madison station.
Louisville is 1h ahead of Galena. It is currently 6:44 PM in Galena and 7:44 PM in Louisville.
Yes, the driving distance between Galena to Louisville is 459 miles. It takes approximately 8h 2m to drive from Galena to Louisville.
What companies run services between Galena, IL, USA and Louisville, KY, USA?
You can take a vehicle from Galena to Louisville Bus Station via Dubuque, Madison, and Indianapolis in around 14h 2m.
- Website
- united.com
Flights from Quad City International Airport to Louisville International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $75–460
Flights from Dane County Regional Airport-Truax Field to Louisville International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 32m
- When
- Every day
- Estimated price
- $100–600
Flights from Chicago O'Hare International Airport to Louisville International Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $65–410
- Website
- aa.com
Flights from Quad City International Airport to Louisville International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 5h 17m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $75–460
Flights from Quad City International Airport to Louisville International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 21m
- When
- Every day
- Estimated price
- $170–750
Flights from Quad City International Airport to Louisville International Airport via Charlotte
- Ave. Duration
- 6h 5m
- When
- Every day
- Estimated price
- $130–650
Flights from Dane County Regional Airport-Truax Field to Louisville International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 5h 34m
- When
- Every day
- Estimated price
- $100–600
Flights from Dane County Regional Airport-Truax Field to Louisville International Airport via Charlotte
- Ave. Duration
- 5h 58m
- When
- Every day
- Estimated price
- $180–900
Flights from Dane County Regional Airport-Truax Field to Louisville International Airport via Reagan Washington
- Ave. Duration
- 7h 51m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $200–950
Flights from Chicago O'Hare International Airport to Louisville International Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $65–410
- Website
- delta.com
Flights from Quad City International Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 5h 24m
- When
- Every day
- Estimated price
- $130–650
Flights from Dane County Regional Airport-Truax Field to Louisville International Airport via Detroit
- Ave. Duration
- 5h 21m
- When
- Every day
- Estimated price
- $130–700
Flights from Dane County Regional Airport-Truax Field to Louisville International Airport via Minneapolis
- Ave. Duration
- 5h 19m
- When
- Every day
- Estimated price
- $160–800
Flights from Dane County Regional Airport-Truax Field to Louisville International Airport via Atlanta
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- $180–850
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $27–60
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $60–130
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $60–130
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Dubuque to Madison
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $30–45
- Book at
- https://www.jeffersonlines.com
- Adult
- $30–45
Bus from Madison to Indianapolis
- Ave. Duration
- 7h 15m
- Frequency
- Once daily
- Estimated price
- $80–120
- Book at
- https://www.jeffersonlines.com
- Adult
- $80–120
Bus from Indianapolis to Louisville Bus Station
- Ave. Duration
- 1h 55m
- Frequency
- Twice daily
- Estimated price
- $35–50
- Book at
- https://www.jeffersonlines.com
- Adult
- $35–50
Bus from Dubuque to Madison
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $30–45
- Book at
- https://www.jeffersonlines.com
- Adult
- $30–45
Bus from UW Madison Campus - N Lake St to Milwaukee Intermodal
- Ave. Duration
- 1h 35m
- Frequency
- Every 4 hours
- Estimated price
- $29–40
- Book at
- https://www.jeffersonlines.com
- Adult
- $29–40
Bus from Indianapolis Union Station to Louisville Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- 4 times a day
- Estimated price
- $35–50
- Book at
- https://www.jeffersonlines.com
- Adult
- $35–50
Bus from Dubuque to Madison
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $30–45
- Book at
- https://www.jeffersonlines.com
- Adult
- $30–45
Bus from Dubuque to Madison
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $30–45
- Book at
- https://www.jeffersonlines.com
- Adult
- $30–45
Bus from Dubuque to Madison
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $30–45
- Book at
- https://www.jeffersonlines.com
- Adult
- $30–45
Bus from Chicago Bus Station to Louisville Bus Station
- Ave. Duration
- 6h 15m
- Frequency
- Every 4 hours
- Estimated price
- $70–110
- Book at
- https://www.jeffersonlines.com
- Adult
- $70–110
Bus from Dubuque to Madison
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $30–45
- Book at
- https://www.jeffersonlines.com
- Adult
- $30–45
Bus from Indianapolis Union Station to Louisville Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- 4 times a day
- Estimated price
- $35–50
- Book at
- https://www.jeffersonlines.com
- Adult
- $35–50
- Phone
- +1 414-266-4409
- [email protected]
- Website
- badgerbus.com
Bus from UW Madison Campus - N Lake St to Milwaukee Intermodal
- Ave. Duration
- 1h 35m
- Frequency
- 5 times a day
- Estimated price
- $23–30
- Website
- https://badgerbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from UW Madison Campus - N Lake St to Milwaukee Intermodal
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $13–25
- Website
- https://www.greyhound.com/
Bus from Indianapolis Union Station to Louisville Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- 5 times a day
- Estimated price
- $18–35
- Website
- https://www.greyhound.com/
Bus from Chicago Bus Station to Louisville Bus Station
- Ave. Duration
- 6h 5m
- Frequency
- 4 times a day
- Estimated price
- $45–90
- Website
- https://www.greyhound.com/
Bus from Indianapolis Union Station to Louisville Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- 5 times a day
- Estimated price
- $18–35
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from UW Madison Campus - N Lake St to Milwaukee Intermodal
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $12–21
- Schedules at
- flixbus.com
Bus from Chicago Bus Station to Louisville Bus Station
- Ave. Duration
- 6h 15m
- Frequency
- Twice daily
- Estimated price
- $45–80
- Schedules at
- flixbus.com
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Indianapolis Union Station to Louisville Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $22–45
Bus from Indianapolis Union Station to Louisville Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $22–45
- Phone
- +1 (866) 912 - 6224
- [email protected]
- Website
- coachusa.com
Bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departures
- Ave. Duration
- 3h
- Frequency
- Hourly
- Estimated price
- $23–50
- Schedules at
- coachusa.com
- Adult
- $23–50
Bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton St
- Ave. Duration
- 4h
- Frequency
- Hourly
- Estimated price
- $26–60
- Schedules at
- coachusa.com
- Adult
- $26–60
Bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton St
- Ave. Duration
- 4h
- Frequency
- Hourly
- Estimated price
- $26–60
- Schedules at
- coachusa.com
- Adult
- $26–60
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