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How to get fromGalena to Louisvilleby car, plane, bus (Greyhound, Flixbus), bus, train, or bus (Amtrak)

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There are 8 ways to get from Galena to Louisville by car, plane, bus (Greyhound, Flixbus), bus, train, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Quad City International Airport, fly

    best
    1. Drive from Galena to Moline-Airport-MLIcar car
    2. Fly from Quad City International Airport (MLI) to Louisville International Airport (SDF)plane plane MLI - SDF
    7h 12m
    $102–576

  2. Drive  456.5 mi

    cheapest
    1. Drive from Galena to Louisvillecar car 456.5 mi
    8h 3m
    $84–121

  3. Bus

    1. Take the bus from Dubuque to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Bus Station to Louisville Bus Stationbus bus
    14h 48m
    $151–240

  4. Bus to Dane County Regional Airport-Truax Field, fly

    1. Take the bus from Dubuque to Madisonbus bus
    2. Fly from Dane County Regional Airport-Truax Field (MSN) to Louisville International Airport (SDF)plane plane MSN - SDF
    9h 41m
    $198–805

  5. Bus, bus to Chicago O'Hare International Airport, fly

    1. Take the bus from Dubuque to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus bus
    3. Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane plane ORD - SDF
    10h 15m
    $174–593

  6. Bus, train

    1. Take the bus from Dubuque to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the train from Chicago Union Station to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Louisville Bus Stationbus bus
    16h 20m
    $183–325

  7. Bus, train via Milwaukee

    1. Take the bus from Dubuque to Madisonbus bus
    2. Take the bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrakbus bus
    3. Take the train from Milwaukee to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to Indianapolistrain train
    5. Take the bus from Indianapolis Union Station to Louisville Bus Stationbus bus
    16h 48m
    $198–355

  8. Bus via Lafayette

    1. Take the bus from Dubuque to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Union Station to Lafayette Amtrak Stationbus bus
    4. Take the bus from Lafayette Amtrak Station to Louisville, KYbus bus
    16h 56m
    $164–255

Quad City International Airport (MLI) to Louisville International Airport (SDF) flights

Calendar82Weekly Planes
Duration5h 33mAverage Duration
Ticket$89Cheapest Price
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Questions & Answers

Map of how to get from Galena to Louisville.ExpandLaunch map view
  • Distance: 433.1 mi
  • Duration: 7h 12m

What companies run services between Galena, IL, USA and Louisville, KY, USA?

You can take a vehicle from Galena to Louisville Bus Station via Dubuque, Madison, 250 N. Lake St - Madison UW Campus, W Jackson Blvd, after S Clinton St, and Chicago Bus Station in around 14h 48m.

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