Rome2Rio

How to get fromGalena to St. Louisby car, plane, bus, or train

Find Transport to St. Louis

See all options

There are 8 ways to get from Galena to St. Louis by car, plane, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Quad City International Airport, fly

    best
    1. Drive from Galena to Moline-Airport-MLIcar car
    2. Fly from Quad City International Airport (MLI) to Lambert–St. Louis International Airport (STL)plane plane MLI - STL
    6h 22m
    $95–498

  2. Drive 319.2 mi

    cheapest
    1. Drive from Galena to St. Louiscar car 319.2 mi
    6h 12m
    $59–85

  3. Drive, bus, train

    1. Drive from Galena to Northern Lights at Epic Staff Ccar car
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the train from Chicago Union Station to St. Louistrain train
    12h 53m
    $123–263

  4. Drive, bus, train via Milwaukee

    1. Drive from Galena to West End at Wildcatcar car
    2. Take the bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrakbus bus
    3. Take the train from Milwaukee to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to St. Louistrain train
    13h 3m
    $133–280

  5. Drive to Dane County Regional Airport-Truax Field, fly

    1. Drive from Galena to Northern Lights at Epic Staff Ccar car
    2. Fly from Dane County Regional Airport-Truax Field (MSN) to Lambert–St. Louis International Airport (STL)plane plane MSN - STL
    8h 11m
    $120–676

  6. Drive, bus to General Mitchell International Airport, fly

    1. Drive from Galena to Northern Lights at Epic Staff Ccar car
    2. Take the bus from Madison, WI-Lake St. to Mitchell Airportbus bus
    3. Fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL)plane plane MKE - STL
    8h 17m
    $512–897

  7. Drive, bus

    1. Drive from Galena to Northern Lights at Epic Staff Ccar car
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus
    14h 9m
    $88–158

  8. Drive, bus via Des Moines (Greyhound)

    1. Drive from Galena to 20 St & 1 Avecar car
    2. Take the bus from Moline Center Station to Des Moinesbus bus
    3. Take the bus from Des Moines to St Louis Bus Stationbus bus
    16h 41m
    $100–192

Quad City International Airport (MLI) to Lambert–St. Louis International Airport (STL) flights

Calendar103Weekly Planes
Duration5h 24mAverage Duration
Ticket$77Cheapest Price
See schedules

Questions & Answers

Map of how to get from Galena to St. Louis.ExpandLaunch map view
  • Distance: 294.4 mi
  • Duration: 6h 22m

What companies run services between Galena, IL, USA and St. Louis, MO, USA?

There is no direct connection from Galena to St. Louis. However, you can drive to Moline-Airport-MLI airport, fly to Lambert–St. Louis International Airport (STL), walk to LAMBERT AIRPORT TERMINAL #1 station, then take the train to CIVIC CENTER station. Alternatively, you can take a vehicle from Galena to St. Louis via Northern Lights at Epic Staff C, W Johnson at East Campus, 250 N. Lake St - Madison UW Campus, W Jackson Blvd, after S Clinton St, and Chicago Union Station in around 12h 53m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound