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How to get fromGare de Lyon-Part-Dieu to Brusselsby train (TGV), train, bus, car, or plane

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There are 7 ways to get from Gare de Lyon-Part-Dieu to Brussels by train (TGV), train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Lyon Part Dieu to Brussel-Zuid / Bruxelles-Miditrain train Tgv
    3h 56m
    €120–260
  2. Train, bus

    cheapest
    1. Take the train from Lyon Part Dieu to Chalon Sur Saonetrain train Ter / ...
    2. Take the bus from Chalon-sur-Saône - Train Station to Brussels - Midi Train Stationbus bus BlaBlaCar Bus
    11h 29m
    €71–136
  3. Drive 666.3 km

    1. Drive from Gare de Lyon-Part-Dieu to Brusselscar car 666.3 km
    7h 30m
    €104–149
  4. Fly Lyon–Saint Exupéry Airport to Brussels Airport

    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Brussels Airport (BRU)plane plane LYS - BRU
    4h 18m
    €98–240
  5. Train to Geneva International Airport, fly to Brussels Airport

    1. Take the train from Lyon Part Dieu to Genevetrain train
    2. Fly from Geneva International Airport (GVA) to Brussels Airport (BRU)plane plane GVA - BRU
    6h 3m
    €86–254
  6. Fly Lyon–Saint Exupéry Airport to Paris Charles De Gaulle Airport, train

    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Paris Charles De Gaulle Airport (CDG)plane plane LYS - CDG
    2. Take the train from Aeroport Cdg2 Tgv Roissy to Brussel-Zuid / Bruxelles-Miditrain train
    5h 6m
    €176–456
  7. Fly Lyon–Saint Exupéry Airport to Amsterdam Airport Schiphol, train

    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Amsterdam Airport Schiphol (AMS)plane plane LYS - AMS
    2. Take the train from Schiphol Airport to Brussel-Zuid / Bruxelles-Miditrain train
    6h 17m
    €171–396

Gare de Lyon-Part-Dieu to Brussels by train

Calendar101Weekly Trains
Duration3h 56mAverage Duration
Ticket€120Cheapest Price
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Questions & Answers

What companies run services between Gare de Lyon-Part-Dieu, France and Brussels, Belgium?

TGV inOui operates a train from Lyon Part Dieu to Brussel-Zuid / Bruxelles-Midi hourly. Tickets cost €150–250 and the journey takes 3h 56m. Belgian Railways (NMBS/SNCB) also services this route twice a week. Alternatively, Brussels Airlines, KLM, and Air Dolomiti fly from Lyon–Saint Exupéry Airport (LYS) to Brussels Airport (BRU) 3 times a day.

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