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How to get fromGare de Lyon-Perrache to Brusselsby train, bus, car, plane, or train (TGV)

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There are 9 ways to get from Gare de Lyon-Perrache to Brussels by train, bus, car, plane, or train (TGV)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Lyon Part Dieu to Bruxelles-Miditrain train Trn
    5h 48m
    €123–254
  2. Bus

    cheapest
    1. Take the bus from Lyon to Brussels-North train stationbus bus N845
    10h 15m
    €60–100
  3. Drive 665.9 km

    1. Drive from Gare de Lyon-Perrache to Brusselscar car 665.9 km
    7h 27m
    €103–149
  4. Fly Lyon–Saint Exupéry Airport to Brussels Airport

    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Brussels Airport (BRU)plane plane LYS - BRU
    4h 12m
    €84–228
  5. Train via Oullins (TGV)

    1. Take the train from Lyon Part Dieu to Brussel-Zuid / Bruxelles-Miditrain train Tgv
    5h 48m
    €152–253
  6. Train #2 (TGV)

    1. Take the train from Lyon Perrache to Brussel-Zuid / Bruxelles-Miditrain train Tgv
    6h 4m
    €151–251
  7. Bus to Geneva International Airport, fly to Brussels Airport

    1. Take the bus from Lyon to Geneva Airportbus bus
    2. Fly from Geneva International Airport (GVA) to Brussels Airport (BRU)plane plane GVA - BRU
    5h 52m
    €70–216
  8. Fly Lyon–Saint Exupéry Airport to Paris Charles De Gaulle Airport, train

    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Paris Charles De Gaulle Airport (CDG)plane plane LYS - CDG
    2. Take the train from Aeroport Cdg2 Tgv Roissy to Brussel-Zuid / Bruxelles-Miditrain train
    5h
    €162–434
  9. Fly Lyon–Saint Exupéry Airport to Amsterdam Airport Schiphol, train

    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Amsterdam Airport Schiphol (AMS)plane plane LYS - AMS
    2. Take the train from Schiphol Airport to Brussel-Zuid / Bruxelles-Miditrain train
    6h 11m
    €157–384

Gare de Lyon-Perrache to Brussels by bus

Calendar5Weekly Buses
Duration10h 15mAverage Duration
Ticket€60Cheapest Price
See schedules

Questions & Answers

What companies run services between Gare de Lyon-Perrache, France and Brussels, Belgium?

Belgian Railways (NMBS/SNCB) operates a train from Lyon Part Dieu to Bruxelles-Midi twice a week. Tickets cost €120–250 and the journey takes 4h. Alternatively, FlixBus operates a bus from Lyon to Brussels-North train station 5 times a week. Tickets cost €60–100 and the journey takes 10h 15m.

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