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How to get fromGatlinburg to Florida Keysby taxi, plane, car, bus, train, or shuttle

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There are 9 ways to get from Gatlinburg to Florida Keys by taxi, plane, car, bus, train, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Mcghee Tyson Airport, fly to Key West International Airport

    best
    1. Take the taxi from Gatlinburg to Mcghee Tyson Airport (TYS)taxi taxi
    2. Fly from Mcghee Tyson Airport (TYS) to Key West International Airport (EYW)plane plane TYS - EYW
    6h 11m
    $350–774

  2. Drive to Asheville Regional Airport, fly to Key West International Airport

    cheapest
    1. Drive from Gatlinburg to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to Key West International Airport (EYW)plane plane AVL - EYW
    6h 54m
    $157–446

  3. Drive, bus

    1. Drive from Gatlinburg to Asheville, NCcar car
    2. Take the bus from Asheville, NC to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte Bus Station to Orlando Bus Stationbus bus
    4. Take the bus from Orlando Bus Station to Miami Airport Stationbus bus
    5. Take the bus from Miami Airport Station to Big Pine Keybus bus
    27h 16m
    $206–345

  4. Drive, bus, train

    1. Drive from Gatlinburg to Asheville, NCcar car
    2. Take the bus from Asheville, NC to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte Bus Station to Fayetteville Bus Stationbus bus
    4. Take the train from Fayetteville Amtrak Station to Miami Amtrak Stationtrain train
    5. Take the bus from Miami Airport Station to Big Pine Keybus bus
    33h 48m
    $415–769

  5. Drive 942.2 mi

    1. Drive from Gatlinburg to Florida Keyscar car 942.2 mi
    19h 3m
    $172–249

  6. Taxi to Mcghee Tyson Airport, fly to Miami International Airport, shuttle

    1. Take the taxi from Gatlinburg to Mcghee Tyson Airport (TYS)taxi taxi
    2. Fly from Mcghee Tyson Airport (TYS) to Miami International Airport (MIA)plane plane TYS - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    8h 51m
    $430–944

  7. Taxi to Mcghee Tyson Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Take the taxi from Gatlinburg to Mcghee Tyson Airport (TYS)taxi taxi
    2. Fly from Mcghee Tyson Airport (TYS) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane TYS - FLL
    3. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle bus
    9h 11m
    $460–1,014

  8. Drive, bus, shuttle

    1. Drive from Gatlinburg to New Leicester Hwy at Walgreenscar car
    2. Take the bus from Asheville, NC to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte Bus Station to Orlando Bus Stationbus bus
    4. Take the bus from Orlando Bus Station to Fort Lauderdale International Airportbus bus
    5. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Summerland Key - Mote Marine Labshuttle bus
    28h 17m
    $362–500

  9. Drive, bus, train via Greensboro

    1. Drive from Gatlinburg to Asheville, NCcar car
    2. Take the bus from Asheville, NC to Greensboro Bus Stopbus bus
    3. Take the train from Greensboro to Carytrain train
    4. Take the train from Cary to Miami Amtrak Stationtrain train
    5. Take the bus from Miami Airport Station to Big Pine Keybus bus
    36h 51m
    $448–874

Mcghee Tyson Airport (TYS) to Key West International Airport (EYW) flights

Calendar26Weekly Planes
Duration4h 32mAverage Duration
Ticket$96Cheapest Price
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Questions & Answers

Map of how to get from Gatlinburg to Florida Keys.ExpandLaunch map view
  • Distance: 849.7 mi
  • Duration: 6h 11m

What companies run services between Gatlinburg, TN, USA and Florida Keys, FL, USA?

There is no direct connection from Gatlinburg to Florida Keys. However, you can take the taxi to Mcghee Tyson Airport (TYS) airport, fly to Key West International Airport (EYW), walk to Key West Airport, take the shuttle to Key West, FL, walk to Whitehead & Eaton, take the bus to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge, then walk to Florida Keys. Alternatively, you can take a vehicle from Gatlinburg to Florida Keys via Asheville, NC, Charlotte Bus Station, Orlando Bus Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 27h 16m.

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