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How to get fromGatlinburg to Florida Keysby taxi, plane, car, bus, train, or shuttle

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There are 7 ways to get from Gatlinburg to Florida Keys by taxi, plane, car, bus, train, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Mcghee Tyson Airport, fly to Key West International Airport

    best
    1. Take the taxi from Gatlinburg to Mcghee Tyson Airport (TYS)taxi taxi
    2. Fly from Mcghee Tyson Airport (TYS) to Key West International Airport (EYW)plane plane TYS - EYW
    6h 4m
    $330–714

  2. Drive to Asheville Regional Airport, fly to Key West International Airport

    cheapest
    1. Drive from Gatlinburg to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to Key West International Airport (EYW)plane plane AVL - EYW
    6h 50m
    $152–456

  3. Drive, bus

    1. Drive from Gatlinburg to Asheville, NCcar car
    2. Take the bus from Asheville, NC to Raleigh Bus Stationbus bus
    3. Take the bus from Raleigh Bus Station to Fayetteville Bus Stationbus bus
    4. Take the bus from Fayetteville Bus Station to Miami Airport Stationbus bus
    5. Take the bus from Miami Airport Station to Big Pine Keybus bus
    31h 32m
    $190–321

  4. Drive, bus, train

    1. Drive from Gatlinburg to Asheville, NCcar car
    2. Take the bus from Asheville, NC to Greensboro Bus Stopbus bus
    3. Take the train from Greensboro to Carytrain train
    4. Take the train from Cary to Miami Amtrak Stationtrain train
    5. Take the bus from Miami Airport Station to Big Pine Keybus bus
    36h 51m
    $339–774

  5. Drive  942.2 mi

    1. Drive from Gatlinburg to Florida Keyscar car 942.2 mi
    19h 4m
    $172–249

  6. Taxi to Mcghee Tyson Airport, fly to Miami International Airport, shuttle

    1. Take the taxi from Gatlinburg to Mcghee Tyson Airport (TYS)taxi taxi
    2. Fly from Mcghee Tyson Airport (TYS) to Miami International Airport (MIA)plane plane TYS - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    8h 46m
    $420–884

  7. Taxi to Mcghee Tyson Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Take the taxi from Gatlinburg to Mcghee Tyson Airport (TYS)taxi taxi
    2. Fly from Mcghee Tyson Airport (TYS) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane TYS - FLL
    3. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle bus
    9h 10m
    $445–964

Mcghee Tyson Airport (TYS) to Key West International Airport (EYW) flights

Calendar16Weekly Planes
Duration3h 27mAverage Duration
Ticket$77Cheapest Price
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Comparing Your Travel Options

Map of how to get from Gatlinburg to Florida Keys.ExpandLaunch map view
  • Distance: 849.7 mi
  • Duration: 6h 4m

What companies run services between Gatlinburg, TN, USA and Florida Keys, FL, USA?

There is no direct connection from Gatlinburg to Florida Keys. However, you can take the taxi to Mcghee Tyson Airport (TYS) airport, fly to Key West International Airport (EYW), walk to Key West Airport, take the shuttle to Key West, FL, walk to Whitehead & Eaton, take the bus to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge, then walk to Florida Keys. Alternatively, you can take a vehicle from Gatlinburg to Florida Keys via Asheville, NC, Raleigh Bus Station, Fayetteville Bus Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 31h 32m.

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