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How to get fromGatlinburg to Panama City Beachby taxi, plane, car, or bus

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There are 6 ways to get from Gatlinburg to Panama City Beach by taxi, plane, car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Mcghee Tyson Airport, fly to Northwest Florida Beaches International Airport

    best
    1. Take the taxi from Gatlinburg to Mcghee Tyson Airport (TYS)taxi taxi
    2. Fly from Mcghee Tyson Airport (TYS) to Northwest Florida Beaches International Airport (ECP)plane plane TYS - ECP
    4h 35m
    $303–745

  2. Drive to Asheville Regional Airport, fly to Destin–Fort Walton Beach Airport, drive

    cheapest
    1. Drive from Gatlinburg to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to Destin–Fort Walton Beach Airport (VPS)plane plane AVL - VPS
    3. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama City Beachcar car
    6h 25m
    $80–368

  3. Drive, bus

    1. Drive from Gatlinburg to Knoxvillecar car
    2. Take the bus from Knoxville to Nashvillebus bus Nyc
    3. Take the bus from Nashville Bus Station to Tallahasseebus bus
    4. Take the bus from Tallahassee to Panama City Beach Bus Stationbus bus
    18h 31m
    $148–260

  4. Drive 485.9 mi

    1. Drive from Gatlinburg to Panama City Beachcar car 485.9 mi
    9h 38m
    $89–129

  5. Taxi to Mcghee Tyson Airport, fly to Destin–Fort Walton Beach Airport, drive

    1. Take the taxi from Gatlinburg to Mcghee Tyson Airport (TYS)taxi taxi
    2. Fly from Mcghee Tyson Airport (TYS) to Destin–Fort Walton Beach Airport (VPS)plane plane TYS - VPS
    3. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama City Beachcar car
    3h 53m
    $263–696

  6. Drive to Asheville Regional Airport, fly to Northwest Florida Beaches International Airport

    1. Drive from Gatlinburg to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to Northwest Florida Beaches International Airport (ECP)plane plane AVL - ECP
    5h 50m
    $120–417

Mcghee Tyson Airport (TYS) to Northwest Florida Beaches International Airport (ECP) flights

Calendar55Weekly Planes
Duration4h 15mAverage Duration
Ticket$79Cheapest Price
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Questions & Answers

Map of how to get from Gatlinburg to Panama City Beach.ExpandLaunch map view
  • Distance: 449.4 mi
  • Duration: 4h 35m

What companies run services between Gatlinburg, TN, USA and Panama City Beach, FL, USA?

There is no direct connection from Gatlinburg to Panama City Beach. However, you can take the taxi to Mcghee Tyson Airport (TYS) airport, fly to Northwest Florida Beaches International Airport (ECP), then take the taxi to Panama City Beach. Alternatively, you can take a vehicle from Gatlinburg to Panama City Beach via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 4Th Ave - Bay 13, Fulton Station Outbound, Nashville Bus Station, Tallahassee, and Panama City Beach Bus Station in around 18h 31m.

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