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How to get fromGenoa to Karlsruheby train (Trenitalia), bus, car, plane, train, or night train

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There are 11 ways to get from Genoa to Karlsruhe by train (Trenitalia), bus, car, plane, train, or night train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Trenitalia)

    best
    1. Take the train from Genova Brignole to Milano Centraletrain train Ic
    2. Take the train from Milano Centrale to Karlsruhe Hbftrain train Ec
    10h 4m
    €102–199

  2. Bus

    cheapest
    1. Take the bus from Genoa to Karlsruhe central train stationbus bus FlixBus N177
    10h 50m
    €55–95

  3. Drive 664.5 km

    1. Drive from Genoa to Karlsruhecar car 664.5 km
    6h 33m
    €104–151

  4. Fly Genoa Cristoforo Colombo Airport to Stuttgart Airport, train

    1. Fly from Genoa Cristoforo Colombo Airport (GOA) to Stuttgart Airport (STR)plane plane GOA - STR
    2. Take the train from Stuttgart Hbf to Karlsruhe Hbftrain train
    7h 7m
    €108–268

  5. Train via Basel

    1. Take the train from Genova Brignole to Milano Centraletrain train Ic
    2. Take the train from Milano Centrale to Basel Sbbtrain train Ec
    3. Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain train 12 / ...
    10h 14m
    €112–304

  6. Train, night train

    1. Take the train from Genova Brignole to Como S.Giovannitrain train
    2. Take the train from Como S. Giovanni to Zürich HBtrain train Ec
    3. Take the night train from Zuerich Hb to Karlsruhe Hbfnighttrain night train Nj
    10h 49m
    €112–340

  7. Train, train to Nice Côte D'Azur International Airport, fly to Strasbourg International Airport

    1. Take the train from Genova P.Za Principe to Ventimigliatrain train
    2. Take the train from Ventimiglia to Saint-Laurent-du-Vartrain train
    3. Fly from Nice Côte D'Azur International Airport (NCE) to Strasbourg International Airport (SXB)plane plane NCE - SXB
    4. Take the train from Strasbourg to Karlsruhe Hbftrain train
    7h 31m
    €89–305

  8. Train, train to Milano Malpensa Airport, fly to Stuttgart Airport

    1. Take the train from Genova Brignole to Milano Centraletrain train
    2. Take the train from Milano Centrale to Malpensa Aeroporto T1train train
    3. Fly from Milano Malpensa Airport (MXP) to Stuttgart Airport (STR)plane plane MXP - STR
    4. Take the train from Stuttgart Hbf to Karlsruhe Hbftrain train
    8h 34m
    €113–291

  9. Train to Turin Caselle Airport, fly to Frankfurt, train

    1. Take the train from Genova Brignole to Torino Lingottotrain train
    2. Fly from Turin Caselle Airport (TRN) to Frankfurt (FRA)plane plane TRN - FRA
    3. Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain train
    8h 22m
    €128–380

  10. Train, train to Milano Malpensa Airport, fly to Frankfurt

    1. Take the train from Genova Brignole to Milano Centraletrain train
    2. Take the train from Milano Centrale to Malpensa Aeroporto T1train train
    3. Fly from Milano Malpensa Airport (MXP) to Frankfurt (FRA)plane plane MXP - FRA
    4. Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain train
    9h 14m
    €100–345

  11. Train, train to Milan Linate Airport, fly to Frankfurt

    1. Take the train from Genova Brignole to Vogheratrain train
    2. Take the train from Voghera to Milano Forlaninitrain train
    3. Fly from Milan Linate Airport (LIN) to Frankfurt (FRA)plane plane LIN - FRA
    4. Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain train
    8h 12m
    €71–271

Genoa to Karlsruhe by train (Trenitalia)

Calendar14Weekly Trains
Duration10h 4mAverage Duration
Ticket€102Cheapest Price
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Questions & Answers

Map of how to get from Genoa to Karlsruhe.ExpandLaunch map view
  • Distance: 735.2 km
  • Duration: 10h 4m

What companies run services between Genoa, Italy and Karlsruhe, Germany?

You can take a train from Genova Brignole to Karlsruhe Hbf via Milano Centrale in around 10h 4m. Alternatively, FlixBus operates a bus from Genoa to Karlsruhe central train station once daily. Tickets cost €55–95 and the journey takes 10h 50m.

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