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How to get fromGenoa to Sienaby train (Trenitalia), bus, or car

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There are 5 ways to get from Genoa to Siena by train (Trenitalia), bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Trenitalia)

    best
    1. Take the train from Genova Brignole to Pisa Centraletrain train Fb / ...
    2. Take the train from Pisa Centrale to Empolitrain train Re
    3. Take the train from Empoli to Sienatrain train Re
    3h 57m
    €29–69
  2. Bus

    cheapest
    1. Take the bus from Genoa to Sienabus bus 516 / ...
    4h
    €24–45
  3. Drive 264 km

    1. Drive from Genoa to Sienacar car 264 km
    3h 20m
    €42–60
  4. Bus via Florence

    1. Take the bus from Genoa to Florence Villa Constanza Bus Stationbus bus 510 / ...
    2. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus N528 / ...
    4h 28m
    €24–46
  5. Bus via Pisa Airport (PSA)

    1. Take the bus from Genoa - Via Fanti d'Italia Bus Stop to Pisa Airportbus bus BlaBlaCar Bus
    2. Take the bus from Pisa Airport to Sienabus bus BlaBlaCar Bus
    6h 30m
    €28–50

Genoa to Siena by train (Trenitalia)

Calendar214Weekly Trains
Duration3h 57mAverage Duration
Ticket€29Cheapest Price
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Questions & Answers

What companies run services between Genoa, Italy and Siena, Italy?

You can take a train from Genova Brignole to Siena via Pisa Centrale and Empoli in around 3h 57m. Alternatively, FlixBus operates a bus from Genoa to Siena twice daily. Tickets cost €24–40 and the journey takes 4h. BlaBlaCar Bus also services this route once daily.

Train operators
Bus operators

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