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How to get fromGrand Central Station to San Diegoby plane, train (Amtrak), bus (Flixbus, Greyhound, Amtrak), car, or train

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There are 6 ways to get from Grand Central Station to San Diego by plane, train (Amtrak), bus (Flixbus, Greyhound, Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Chicago O'Hare International Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to San Diego International Airport (SAN)plane plane ORD - SAN
    6h 7m
    $142–605

  2. Train (Amtrak)

    1. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train Southwest Chief
    2. Take the train from Fullerton Amtrak Station to San Diegotrain train Pacific Surfliner
    46h 18m
    $711–1,503

  3. Bus

    1. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Los Angeles Union Stationbus bus
    3. Take the bus from Los Angeles to San Diegobus bus
    2d 3h
    $369–689

  4. Drive 2,075 mi

    1. Drive from Grand Central Station to San Diegocar car 2,075 mi
    32h 35m
    $379–547

  5. Fly from Chicago Midway International Airport

    1. Fly from Chicago Midway International Airport (MDW) to San Diego International Airport (SAN)plane plane MDW - SAN
    5h 51m
    $172–755

  6. Train to General Mitchell International Airport, fly

    1. Take the train from Chicago Union Station to Milwaukeetrain train
    2. Fly from General Mitchell International Airport (MKE) to San Diego International Airport (SAN)plane plane MKE - SAN
    7h 16m
    $228–969

Grand Central Station to San Diego by foot and train (Amtrak)

Calendar7Weekly Services
Duration46h 18mAverage Duration
Ticket$711Cheapest Price
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Questions & Answers

Map of how to get from Grand Central Station to San Diego.ExpandLaunch map view
  • Distance: 1,738.9 mi
  • Duration: 6h 7m

What companies run services between Grand Central Station, IL, USA and San Diego, CA, USA?

American Airlines, United Airlines, and Alaska Airlines, Inc. fly from Chicago O'Hare International Airport (ORD) to San Diego International Airport (SAN) hourly. Alternatively, you can take a vehicle from Grand Central Station to San Diego via Chicago Union Station and Fullerton Amtrak Station in around 46h 18m.

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