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How to get fromGrand Central Terminal to Knoxvilleby plane, bus, car, or train

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There are 8 ways to get from Grand Central Terminal to Knoxville by plane, bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Laguardia Airport to Mcghee Tyson Airport

    best
    1. Fly from Laguardia Airport (LGA) to Mcghee Tyson Airport (TYS)plane plane LGA - TYS
    4h 22m
    $223–936

  2. Fly Newark Liberty International Airport to Asheville Regional Airport, drive

    cheapest
    1. Fly from Newark Liberty International Airport (EWR) to Asheville Regional Airport (AVL)plane plane EWR - AVL
    2. Drive from Asheville-Airport-AVL to Knoxvillecar car
    6h 2m
    $107–432

  3. Bus

    1. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    13h 33m
    $138–163

  4. Drive 704.5 mi

    1. Drive from Grand Central Terminal to Knoxvillecar car 704.5 mi
    12h 3m
    $129–186

  5. Fly Newark Liberty International Airport to Mcghee Tyson Airport

    1. Fly from Newark Liberty International Airport (EWR) to Mcghee Tyson Airport (TYS)plane plane EWR - TYS
    4h 16m
    $195–797

  6. Fly Laguardia Airport to Chattanooga Metropolitan Airport, drive

    1. Fly from Laguardia Airport (LGA) to Chattanooga Metropolitan Airport (CHA)plane plane LGA - CHA
    2. Drive from Chattanooga Metropolitan Airport (CHA) to Knoxvillecar car
    5h 54m
    $206–994

  7. Train to Philadelphia International Airport, fly to Mcghee Tyson Airport

    1. Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Mcghee Tyson Airport (TYS)plane plane PHL - TYS
    5h 42m
    $239–1,569

  8. Fly Laguardia Airport to Asheville Regional Airport, drive

    1. Fly from Laguardia Airport (LGA) to Asheville Regional Airport (AVL)plane plane LGA - AVL
    2. Drive from Asheville-Airport-AVL to Knoxvillecar car
    6h 6m
    $115–511

Laguardia Airport (LGA) to Mcghee Tyson Airport (TYS) flights

Calendar86Weekly Planes
Duration3h 53mAverage Duration
Ticket$161Cheapest Price
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Questions & Answers

Map of how to get from Grand Central Terminal to Knoxville.ExpandLaunch map view
  • Distance: 673.2 mi
  • Duration: 4h 22m

What companies run services between Grand Central Terminal, NY, USA and Knoxville, TN, USA?

American Airlines, Delta, and United Airlines fly from Laguardia Airport (LGA) to Mcghee Tyson Airport (TYS) every 2 hours. Alternatively, NYTN Bus operates a bus from New York, NY to Knoxville, TN once daily. Tickets cost $95–110 and the journey takes 12h.

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