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How to get fromGrand Junction to Mayo Clinicby car, plane, bus, bus (Greyhound), or train

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There are 9 ways to get from Grand Junction to Mayo Clinic by car, plane, bus, bus (Greyhound), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Montrose Regional Airport, fly to Minneapolis–Saint Paul International Airport, bus

    best
    1. Drive from Grand Junction to Montrose-Airport-MTJcar car
    2. Fly from Montrose Regional Airport (MTJ) to Minneapolis–Saint Paul International Airport (MSP)plane plane MTJ - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    8h 10m
    $161–615

  2. Fly Grand Junction Regional Airport to Rochester

    cheapest
    1. Fly from Grand Junction Regional Airport (GJT) to Rochester (RST)plane plane GJT - RST
    10h 24m
    $87–492

  3. Bus

    1. Take the bus from Grand Junction Downtown Transfer Facility to Union Stationbus bus
    2. Take the bus from Denver Union Station to Des Moinesbus bus
    3. Take the bus from Des Moines to Minneapolis Bus Stationbus bus
    4. Take the bus from Minneapolis to Rochesterbus bus
    28h 38m
    $212–340

  4. Train, bus via Madison

    1. Take the train from Grand Junction Amtrak Station to Chicago Union Stationtrain train
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    37h 32m
    $434–1,038

  5. Drive  1,070.2 mi

    1. Drive from Grand Junction to Mayo Cliniccar car 1,070.2 mi
    18h 13m
    $196–283

  6. Fly Grand Junction Regional Airport to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Grand Junction Regional Airport (GJT) to Minneapolis–Saint Paul International Airport (MSP)plane plane GJT - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    8h 50m
    $151–602

  7. Bus, bus to Eagle County Regional Airport, fly to Rochester

    1. Take the bus from Grand Junction Downtown Transfer Facility to Vail Transportation Centerbus bus
    2. Take the bus from Vail Transportation Center to Eagle County Airportbus bus
    3. Fly from Eagle County Regional Airport (EGE) to Rochester (RST)plane plane EGE - RST
    14h 56m
    $164–576

  8. Bus via Sioux Falls

    1. Take the bus from Grand Junction Downtown Transfer Facility to Union Stationbus bus
    2. Take the bus from Denver to Omahabus bus
    3. Take the bus from Omaha to Sioux Fallsbus bus
    4. Take the bus from Sioux Falls to Minneapolis-St. Paulbus bus
    5. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    33h 26m
    $362–465

  9. Train, bus

    1. Take the train from Grand Junction Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    3. Take the bus from St. Paul to Rochesterbus bus
    38h 50m
    $497–1,238

Grand Junction to Mayo Clinic by bus and foot

Calendar7Weekly Services
Duration28h 38mAverage Duration
Ticket$212Cheapest Price
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Comparing Your Travel Options

Map of how to get from Grand Junction to Mayo Clinic.ExpandLaunch map view
  • Distance: 1,014.4 mi
  • Duration: 8h 10m

What companies run services between Grand Junction, CO, USA and Mayo Clinic, MN, USA?

You can take a bus from Grand Junction Downtown Transfer Facility to Mayo Clinic via Denver Union Station, Des Moines, Minneapolis, and Rochester in around 28h 38m. Alternatively, American Airlines, United Airlines, and Delta fly from Grand Junction Regional Airport (GJT) to Rochester (RST) every 4 hours.

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