There are 4 ways to get from Great Falls to Mayo Clinic by plane, bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly, bus
best- Fly from Great Falls International Airport (GTF) to Minneapolis–Saint Paul International Airport (MSP)plane GTF - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
8h 7m$275–1,020Drive 1,050.1 mi
cheapest- Drive from Great Falls to Mayo Cliniccar 1,050.1 mi
16h 46m$192–277Bus, train
- Take the bus from Great Falls Transfer Center to Shelby Amtrak Stationbus
- Take the train from Shelby Amtrak Station to St. Paul-Minneapolistrain
- Take the bus from St. Paul to Rochester, MNbus
25h 33m$368–740Bus
- Take the bus from Great Falls Transfer Center to Butte, MTbus
- Take the bus from Butte to Billingsbus
- Take the bus from Billings to Minneapolisbus
- Take the bus from Minneapolis Bus Depot to Rochester, MNbus
26h 53m$298–458
Great Falls International Airport (GTF) to Minneapolis–Saint Paul International Airport (MSP) flights
Questions & Answers
The cheapest way to get from Great Falls to Mayo Clinic is to drive which costs $190 - $280 and takes 16h 46m.
The fastest way to get from Great Falls to Mayo Clinic is to fly and bus which takes 8h 7m and costs $270 - $1,100.
No, there is no direct bus from Great Falls to Mayo Clinic. However, there are services departing from Great Falls Transfer Center and arriving at Rochester, MN via Butte, Billings and Minneapolis Bus Depot. The journey, including transfers, takes approximately 26h 53m.
The distance between Great Falls and Mayo Clinic is 970 miles. The road distance is 1056.2 miles.
The best way to get from Great Falls to Mayo Clinic without a car is to bus and train which takes 25h 33m and costs $360 - $750.
It takes approximately 8h 7m to get from Great Falls to Mayo Clinic, including transfers.
Great Falls to Mayo Clinic bus services, operated by Salt Lake Express, depart from Great Falls Transfer Center station.
Great Falls to Mayo Clinic bus services, operated by Salt Lake Express, arrive at Butte, MT station.
Yes, the driving distance between Great Falls to Mayo Clinic is 1056 miles. It takes approximately 16h 46m to drive from Great Falls to Mayo Clinic.
There are 75+ hotels available in Mayo Clinic.
What companies run services between Great Falls, MT, USA and Mayo Clinic, MN, USA?
You can take a bus from Great Falls Transfer Center to Mayo Clinic via Butte, Billings, Minneapolis, Minneapolis Bus Depot, and Rochester in around 26h 53m.
- Website
- delta.com
Flights from Great Falls International Airport to Minneapolis–Saint Paul International Airport via Salt Lake City
- Ave. Duration
- 5h 48m
- When
- Every day
- Estimated price
- $240–1,100
- Website
- united.com
Flights from Great Falls International Airport to Minneapolis–Saint Paul International Airport via Denver
- Ave. Duration
- 5h 22m
- When
- Every day
- Estimated price
- $220–1,000
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Shelby Amtrak Station to St. Paul-Minneapolis
- Ave. Duration
- 20h 5m
- Frequency
- Twice daily
- Estimated price
- $340–700
- Website
- https://www.amtrak.com/home.html
- Phone
- + 1 507-280-9270
- Website
- groometransportation.com
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- https://groometransportation.com/minneapolis-st-paul-airport/rochester
- Phone
- +1 406-470-0727
- [email protected]
- Website
- northern.rural-transit.com
Bus from Great Falls Transfer Center to Shelby Amtrak Station
- Ave. Duration
- 1h 50m
- Frequency
- 4 times a week
- Schedules at
- northern.rural-transit.com
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from St. Paul to Rochester, MN
- Ave. Duration
- 1h 30m
- Frequency
- 3 times a day
- Estimated price
- $28–40
- Book at
- https://www.jeffersonlines.com
- Adult
- $28–40
Bus from Butte to Billings
- Ave. Duration
- 3h 35m
- Frequency
- 4 times a day
- Estimated price
- $55–85
- Book at
- https://www.jeffersonlines.com
- Adult
- $55–85
Bus from Billings to Minneapolis
- Ave. Duration
- 14h 50m
- Frequency
- Twice daily
- Estimated price
- $180–260
- Book at
- https://www.jeffersonlines.com
- Adult
- $180–260
Bus from Minneapolis Bus Depot to Rochester, MN
- Ave. Duration
- 2h 20m
- Frequency
- 3 times a day
- Estimated price
- $30–45
- Book at
- https://www.jeffersonlines.com
- Adult
- $30–45
- Phone
- +1 208-656-8824
- [email protected]
- Website
- saltlakeexpress.com
Bus from Great Falls Transfer Center to Butte, MT
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- $30–70
- Website
- https://saltlakeexpress.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide















