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How to get fromGreat Smoky Mountains to Durhamby car, bus, plane, or train

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There are 6 ways to get from Great Smoky Mountains to Durham by car, bus, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive, bus

    best
    1. Drive from Great Smoky Mountains to Asheville, NCcar car
    2. Take the bus from Asheville, NC to Greensboro Bus Stopbus bus
    3. Take the bus from Greensboro Bus Stop to Durhambus bus
    7h 13m
    $48–86

  2. Drive, bus via N Columbia St at W Franklin St

    cheapest
    1. Drive from Great Smoky Mountains to New Leicester Hwy at Walgreenscar car
    2. Take the bus from Asheville, NC to Greensboro Bus Stopbus bus
    3. Take the bus from Greensboro Depot to N Columbia St at W Franklin Stbus bus 4
    10h 3m
    $46–76

  3. Drive 296.5 mi

    1. Drive from Great Smoky Mountains to Durhamcar car 296.5 mi
    5h 46m
    $55–79

  4. Drive to Asheville Regional Airport, fly

    1. Drive from Great Smoky Mountains to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to Raleigh-Durham International Airport (RDU)plane plane AVL - RDU
    6h 31m
    $66–357

  5. Drive, bus, train

    1. Drive from Great Smoky Mountains to Asheville, NCcar car
    2. Take the bus from Asheville, NC to Greensboro Bus Stopbus bus
    3. Take the train from Greensboro to Durham Amtrak Stationtrain train
    7h 19m
    $57–110

  6. Drive to Mcghee Tyson Airport, fly

    1. Drive from Great Smoky Mountains to Mcghee Tyson Airport (TYS)car car
    2. Fly from Mcghee Tyson Airport (TYS) to Raleigh-Durham International Airport (RDU)plane plane TYS - RDU
    6h 40m
    $97–572

Asheville Regional Airport (AVL) to Raleigh-Durham International Airport (RDU) flights

Calendar86Weekly Planes
Duration4h 6mAverage Duration
Ticket$49Cheapest Price
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Questions & Answers

Map of how to get from Great Smoky Mountains to Durham.ExpandLaunch map view
  • Distance: 300.1 mi
  • Duration: 7h 13m

What companies run services between Great Smoky Mountains, TN, USA and Durham, NC, USA?

There is no direct connection from Great Smoky Mountains to Durham. However, you can drive to Asheville, NC, take the bus to Greensboro Bus Stop, then take the bus to Durham. Alternatively, you can drive from Great Smoky Mountains to Durham in around 5h 46m.

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Train operators
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