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How to get fromGreat Smoky Mountains to Pensacolaby car, plane, taxi, or bus

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There are 8 ways to get from Great Smoky Mountains to Pensacola by car, plane, taxi, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Mcghee Tyson Airport, fly to Destin–Fort Walton Beach Airport, taxi

    best
    1. Drive from Great Smoky Mountains to Mcghee Tyson Airport (TYS)car car
    2. Fly from Mcghee Tyson Airport (TYS) to Destin–Fort Walton Beach Airport (VPS)plane plane TYS - VPS
    3. Take the taxi from Destin–Fort Walton Beach Airport (VPS) to Pensacolataxi taxi
    4h 24m
    $206–636

  2. Drive to Asheville Regional Airport, fly to Pensacola International Airport

    cheapest
    1. Drive from Great Smoky Mountains to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to Pensacola International Airport (PNS)plane plane AVL - PNS
    6h 46m
    $67–323

  3. Drive, bus

    1. Drive from Great Smoky Mountains to New Leicester Hwy at Walgreenscar car
    2. Drive from ART Station to Taqueria Guadalajara - Greenvillecar car
    3. Take the bus from Taqueria Guadalajara - Greenville to Atlantabus bus
    4. Take the bus from Atlanta to Mobilebus bus
    5. Take the bus from Loxley to Pensacolabus bus
    15h 40m
    $183–340

  4. Drive 505.6 mi

    1. Drive from Great Smoky Mountains to Pensacolacar car 505.6 mi
    9h 29m
    $93–134

  5. Drive to Mcghee Tyson Airport, fly to Pensacola International Airport

    1. Drive from Great Smoky Mountains to Mcghee Tyson Airport (TYS)car car
    2. Fly from Mcghee Tyson Airport (TYS) to Pensacola International Airport (PNS)plane plane TYS - PNS
    6h 12m
    $83–448

  6. Drive to Asheville Regional Airport, fly to Destin–Fort Walton Beach Airport, taxi

    1. Drive from Great Smoky Mountains to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to Destin–Fort Walton Beach Airport (VPS)plane plane AVL - VPS
    3. Take the taxi from Destin–Fort Walton Beach Airport (VPS) to Pensacolataxi taxi
    6h 19m
    $190–501

  7. Drive, bus via Nashville

    1. Drive from Great Smoky Mountains to Knoxvillecar car
    2. Take the bus from Knoxville to Nashvillebus bus Nyc
    3. Take the bus from Omni Nashville Hotel to Grand Hyatt Atlanta in Buckheadbus bus
    4. Take the bus from Atlanta to Mobilebus bus
    5. Take the bus from Loxley to Pensacolabus bus
    18h 11m
    $343–444

  8. Drive, bus via Winston-Salem

    1. Drive from Great Smoky Mountains to Asheville, NCcar car
    2. Take the bus from Asheville, NC to Winston Salem(Trans Center)bus bus
    3. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    4. Take the bus from Charlotte Bus Station to Atlanta Bus Stationbus bus
    5. Take the bus from Atlanta Bus Station to La Grange Bus Stationbus bus
    6. Take the bus from La Grange Bus Station to Mobilebus bus
    7. Take the bus from Loxley to Pensacolabus bus
    20h 20m
    $196–315

Mcghee Tyson Airport (TYS) to Destin–Fort Walton Beach Airport (VPS) flights

Calendar17Weekly Planes
Duration3h 9mAverage Duration
Ticket$79Cheapest Price
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Questions & Answers

Map of how to get from Great Smoky Mountains to Pensacola.ExpandLaunch map view
  • Distance: 503.5 mi
  • Duration: 4h 24m

What companies run services between Great Smoky Mountains, TN, USA and Pensacola, FL, USA?

There is no direct connection from Great Smoky Mountains to Pensacola. However, you can drive to Mcghee Tyson Airport (TYS) airport, fly to Destin–Fort Walton Beach Airport (VPS), then take the taxi to Pensacola. Alternatively, you can take a vehicle from Great Smoky Mountains to Pensacola via New Leicester Hwy at Walgreens, ART Station, Taqueria Guadalajara - Greenville, Atlanta, Shallowford Rd @ New Peachtree, Doraville Station - Bay F, Atlanta, and Loxley in around 15h 40m.

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