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How to get fromGreen Bay to Mayo Clinicby bus, car, or plane

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There are 5 ways to get from Green Bay to Mayo Clinic by bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Green Bay station to La Crosse Grand River Stationbus bus Green Bay
    2. Take the bus from La Crosse to Rochester, MNbus bus Milwaukee / ...
    8h 3m
    $67–83

  2. Drive 260.5 mi

    cheapest
    1. Drive from Green Bay to Mayo Cliniccar car 260.5 mi
    5h 12m
    $48–69

  3. Fly Green Bay to Rochester

    1. Fly from Green Bay (GRB) to Rochester (RST)plane plane GRB - RST
    5h 16m
    $84–389

  4. Fly Green Bay to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Green Bay (GRB) to Minneapolis–Saint Paul International Airport (MSP)plane plane GRB - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    4h 23m
    $140–451

  5. Bus to Appleton International Airport, fly to Rochester

    1. Take the bus from Green Bay station to Appleton Valley Transitbus bus
    2. Fly from Appleton International Airport (ATW) to Rochester (RST)plane plane ATW - RST
    7h 15m
    $66–377

Green Bay to Mayo Clinic by bus and foot

Calendar7Weekly Services
Duration8h 3mAverage Duration
Ticket$67Cheapest Price
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Questions & Answers

Map of how to get from Green Bay to Mayo Clinic.ExpandLaunch map view
  • Distance: 288.8 mi
  • Duration: 8h 3m

What companies run services between Green Bay, WI, USA and Mayo Clinic, MN, USA?

You can take a bus from Green Bay station to Mayo Clinic via La Crosse Grand River Station, La Crosse, and Rochester in around 8h 3m. Alternatively, United Airlines, Delta, and American Airlines fly from Green Bay (GRB) to Rochester (RST) every 3 hours.

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