There are 9 ways to get from Greeneville to Des Moines by taxi, plane, shuttle, bus, car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi to Tri-Cities Regional Tn/Va Airport, fly
best- Take the taxi from Greeneville to Tri-Cities-Regional-Airport-TRItaxi
- Fly from Tri-Cities Regional Tn/Va Airport (TRI) to Des Moines (DSM)plane TRI - DSM
5h 26m$196–554Drive to Mcghee Tyson Airport, fly
cheapest- Drive from Greeneville to Mcghee Tyson Airport (TYS)car
- Fly from Mcghee Tyson Airport (TYS) to Des Moines (DSM)plane TYS - DSM
5h 47m$102–433Shuttle, bus
- Take a shuttle bus from Allen Gap, TN to Black Bear Resort
- Take a shuttle bus from Black Bear Resort to Boone
- Take the bus from Boone to Winston-Salembus
- Take the bus from Winston Salem to Columbusbus
- Take the bus from Columbus to Chicagobus
- Take the bus from Chicago Bus Station to Des Moinesbus
35h 5m$401–552Drive, bus, train
- Drive from Greeneville to Asheville, NCcar
- Take the bus from Asheville, NC to Greensboro Bus Stopbus
- Take the train from Greensboro to Charlottesvilletrain
- Take the train from Charlottesville to Indianapolistrain
- Take the bus from Indianapolis Union Station to Des Moinesbus
36h 18m$544–894Drive 840.8 mi
- Drive from Greeneville to Des Moinescar 840.8 mi
15h 19m$144–208Drive to Asheville Regional Airport, fly
- Drive from Greeneville to ART Stationcar
- Fly from Asheville Regional Airport (AVL) to Des Moines (DSM)plane AVL - DSM
7h 43m$108–458Drive, bus, train via Galesburg
- Drive from Greeneville to Asheville, NCcar
- Take the bus from Asheville, NC to Greensboro Bus Stopbus
- Take the train from Greensboro to Raleigh Union Stationtrain
- Take the train from Raleigh Union Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain
- Take the bus from Galesburg to Des Moinesbus
42h 21m$749–1,234Taxi, bus
- Take the taxi from Greeneville to Johnson City, TNtaxi
- Take the bus from Johnson City, TN to New York, NYbus Ny
- Take the bus from New York City Chinatown to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Des Moinesbus
42h 47m$385–545Drive, bus, train via Chicago
- Drive from Greeneville to Asheville, NCcar
- Take the bus from Asheville, NC to Greensboro Bus Stopbus
- Take the train from Greensboro to Carytrain
- Take the train from Cary to Chicago Union Stationtrain
- Take the bus from Chicago Bus Station to Des Moinesbus
42h 53m$684–1,174
Tri-Cities Regional Tn/Va Airport (TRI) to Des Moines (DSM) flights
Comparing Your Travel Options
The cheapest way to get from Greeneville to Des Moines is to drive which costs $140 - $210 and takes 15h 19m.
The fastest way to get from Greeneville to Des Moines is to taxi and fly which takes 5h 26m and costs $190 - $600.
The distance between Greeneville and Des Moines is 743 miles. The road distance is 845.8 miles.
The best way to get from Greeneville to Des Moines without a car is to shuttle and bus which takes 35h 5m and costs $400 - $550.
It takes approximately 5h 26m to get from Greeneville to Des Moines, including transfers.
Des Moines is 1h behind Greeneville. It is currently 3:31 PM in Greeneville and 2:31 PM in Des Moines.
Yes, the driving distance between Greeneville to Des Moines is 846 miles. It takes approximately 15h 19m to drive from Greeneville to Des Moines.
There are 240+ hotels available in Des Moines.
What companies run services between Greeneville, TN, USA and Des Moines, IA, USA?
There is no direct connection from Greeneville to Des Moines. However, you can take the taxi to Tri-Cities-Regional-Airport-TRI airport, fly to Des Moines (DSM), then take the taxi to Des Moines. Alternatively, you can take a vehicle from Greeneville to Des Moines via Allen Gap, TN, Black Bear Resort, Boone, Boone, Winston Salem, Columbus, and Chicago Bus Station in around 35h 5m.
- Website
- aa.com
Flights from Tri-Cities Regional Tn/Va Airport to Des Moines via Charlotte
- Ave. Duration
- 4h 54m
- When
- Every day
- Estimated price
- $85–440
Flights from Tri-Cities Regional Tn/Va Airport to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 8h 17m
- When
- Every day
- Estimated price
- $120–550
Flights from Tri-Cities Regional Tn/Va Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 8h 28m
- When
- Every day
- Estimated price
- $75–410
Flights from Mcghee Tyson Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 6h 33m
- When
- Every day
- Estimated price
- $75–410
Flights from Asheville Regional Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 7h 20m
- When
- Every day
- Estimated price
- $80–420
Flights from Asheville Regional Airport to Des Moines via Charlotte
- Ave. Duration
- 5h 42m
- When
- Every day
- Estimated price
- $85–430
Flights from Asheville Regional Airport to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 7h 47m
- When
- Every day
- Estimated price
- $110–550
Flights from Asheville Regional Airport to Des Moines via Reagan Washington
- Ave. Duration
- 8h 47m
- When
- Saturday
- Estimated price
- $100–500
- Website
- delta.com
Flights from Tri-Cities Regional Tn/Va Airport to Des Moines via Atlanta
- Ave. Duration
- 5h 13m
- When
- Every day
- Estimated price
- $85–440
Flights from Mcghee Tyson Airport to Des Moines via Atlanta
- Ave. Duration
- 4h 43m
- When
- Every day
- Estimated price
- $85–430
Flights from Mcghee Tyson Airport to Des Moines via Detroit
- Ave. Duration
- 6h 4m
- When
- Saturday and Sunday
- Estimated price
- $85–440
Flights from Mcghee Tyson Airport to Des Moines via Minneapolis
- Ave. Duration
- 7h 4m
- When
- Every day
- Estimated price
- $90–450
Flights from Asheville Regional Airport to Des Moines via Atlanta
- Ave. Duration
- 5h 20m
- When
- Every day
- Estimated price
- $85–430
Flights from Asheville Regional Airport to Des Moines via Minneapolis
- Ave. Duration
- 8h 45m
- When
- Saturday
- Estimated price
- $95–460
- Website
- united.com
Flights from Mcghee Tyson Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $75–410
Flights from Asheville Regional Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 13m
- When
- Every day
- Estimated price
- $80–420
- Website
- allegiantair.com
Flights from Asheville Regional Airport to Des Moines via Orlando Sanford
- Ave. Duration
- 7h
- When
- Monday and Saturday
- Estimated price
- $120–550
- Website
- southwest.com
Flights from Mcghee Tyson Airport to Des Moines via Nashville
- Ave. Duration
- 4h 5m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $70–390
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Greensboro to Charlottesville
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- $90–150
- Website
- Amtrak
Train from Charlottesville to Indianapolis
- Ave. Duration
- 15h 23m
- Frequency
- 3 times a week
- Estimated price
- $330–550
- Website
- Amtrak
Train from Greensboro to Raleigh Union Station
- Ave. Duration
- 1h 42m
- Frequency
- 5 times a day
- Estimated price
- $40–70
- Website
- Amtrak
Train from Raleigh Union Station to Chicago Union Station
- Ave. Duration
- 24h 28m
- Frequency
- Once daily
- Estimated price
- $550–900
- Website
- Amtrak
Train from Chicago Union Station to Galesburg Amtrak Station
- Ave. Duration
- 2h 36m
- Frequency
- 4 times a day
- Estimated price
- $85–140
- Website
- Amtrak
Train from Greensboro to Cary
- Ave. Duration
- 1h 27m
- Frequency
- 5 times a day
- Estimated price
- $35–65
- Website
- Amtrak
Train from Cary to Chicago Union Station
- Ave. Duration
- 25h 12m
- Frequency
- Once daily
- Estimated price
- $550–950
- Website
- Amtrak
- Phone
- +1-423-725-5988
- Website
- Black Bear Resort Shuttle
Shuttle from Allen Gap, TN to Black Bear Resort
- Ave. Duration
- 1h 30m
- Frequency
- On demand
- Estimated price
- $122
- Website
- Black Bear Resort Shuttle
Shuttle from Black Bear Resort to Boone
- Ave. Duration
- 1h
- Frequency
- On demand
- Estimated price
- $86
- Website
- Black Bear Resort Shuttle
- Phone
- +1 704-348-1200
- [email protected]
- Website
- Sunway Charters
Bus from Boone to Winston-Salem
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $15–22
- Schedules at
- Sunway Charters
- Passenger
- $15–22
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Winston Salem to Columbus
- Ave. Duration
- 9h 40m
- Frequency
- Once daily
- Estimated price
- $40–90
- Website
- Barons Bus
Bus from Columbus to Chicago
- Ave. Duration
- 7h 15m
- Frequency
- Twice daily
- Estimated price
- $30–80
- Website
- Barons Bus
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 8h 25m
- Frequency
- 5 times a day
- Estimated price
- $60–95
- Website
- Greyhound
Bus from Asheville, NC to Greensboro Bus Stop
- Ave. Duration
- 3h 20m
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- Greyhound
Bus from Indianapolis Union Station to Des Moines
- Ave. Duration
- 9h 50m
- Frequency
- Twice daily
- Estimated price
- $85–130
- Website
- Greyhound
Bus from Asheville, NC to Greensboro Bus Stop
- Ave. Duration
- 3h 20m
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- Greyhound
Bus from Galesburg to Des Moines
- Ave. Duration
- 4h 55m
- Frequency
- Twice daily
- Estimated price
- $35–60
- Website
- Greyhound
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 8h 25m
- Frequency
- 5 times a day
- Estimated price
- $60–95
- Website
- Greyhound
Bus from Asheville, NC to Greensboro Bus Stop
- Ave. Duration
- 3h 20m
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- Greyhound
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 8h 25m
- Frequency
- 5 times a day
- Estimated price
- $60–95
- Website
- Greyhound
- Phone
- +1 615-939-8887
- [email protected]
- Website
- New York to Tennessee Bus
Bus from Johnson City, TN to New York, NY
- Ave. Duration
- 10h 30m
- Frequency
- Once daily
- Estimated price
- $90–110
- Website
- New York to Tennessee Bus
- Adult One-way
- $90–110
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from New York City Chinatown to Chicago Bus Station
- Ave. Duration
- 21h 10m
- Frequency
- Twice daily
- Estimated price
- $150–240
- Schedules at
- Flixbus USA
- Ave. Duration
- 47 min
- Estimated price
- $85–130
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