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How to get fromGreeneville to Des Moinesby taxi, plane, car, bus, or train

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There are 8 ways to get from Greeneville to Des Moines by taxi, plane, car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Tri-Cities Regional Tn/Va Airport, fly

    best
    1. Take the taxi from Greeneville to Tri-Cities-Regional-Airport-TRItaxi taxi
    2. Fly from Tri-Cities Regional Tn/Va Airport (TRI) to Des Moines (DSM)plane plane TRI - DSM
    5h 13m
    $210–622

  2. Drive 840.8 mi

    cheapest
    1. Drive from Greeneville to Des Moinescar car 840.8 mi
    15h 19m
    $154–222

  3. Drive, bus

    1. Drive from Greeneville to Charlie Haun WB Aft Washington PKcar car
    2. Take the bus from Knoxville to Nashvillebus bus Nyc
    3. Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus bus
    4. Take the bus from Carbondale to St. Louisbus bus
    5. Take the bus from St Louis Bus Station to Des Moinesbus bus
    24h 20m
    $222–382

  4. Drive to Mcghee Tyson Airport, fly

    1. Drive from Greeneville to Mcghee Tyson Airport (TYS)car car
    2. Fly from Mcghee Tyson Airport (TYS) to Des Moines (DSM)plane plane TYS - DSM
    5h 49m
    $182–843

  5. Drive to Asheville Regional Airport, fly

    1. Drive from Greeneville to ART Stationcar car
    2. Fly from Asheville Regional Airport (AVL) to Des Moines (DSM)plane plane AVL - DSM
    7h 34m
    $158–686

  6. Drive to Greenville–Spartanburg International Airport, fly

    1. Drive from Greeneville to Greenville–Spartanburg International Airport (GSP)car car
    2. Fly from Greenville–Spartanburg International Airport (GSP) to Des Moines (DSM)plane plane GSP - DSM
    7h 15m
    $189–852

  7. Drive, bus, train

    1. Drive from Greeneville to Bristol Exit 5 Park & Ride Lotcar car
    2. Take the bus from Bristol Exit 5 Park & Ride Lot to Wytheville Rural King Parking Lotbus bus
    3. Take the bus from Wytheville to Ashlandbus bus
    4. Take the train from Ashland Amtrak Station to Indianapolistrain train
    5. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    26h 52m
    $209–423

  8. Drive, bus via Columbus

    1. Drive from Greeneville to Asheville, NCcar car
    2. Take the bus from Asheville, NC to Winston Salem(Trans Center)bus bus
    3. Take the bus from Winston Salem(Trans Center) to Columbus - Mound Stbus bus
    4. Take the bus from Columbus to Indianapolis Union Stationbus bus
    5. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    30h 15m
    $156–325

Tri-Cities Regional Tn/Va Airport (TRI) to Des Moines (DSM) flights

Calendar64Weekly Planes
Duration5h 52mAverage Duration
Ticket$93Cheapest Price
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Questions & Answers

Map of how to get from Greeneville to Des Moines.ExpandLaunch map view
  • Distance: 738.6 mi
  • Duration: 5h 13m

What companies run services between Greeneville, TN, USA and Des Moines, IA, USA?

There is no direct connection from Greeneville to Des Moines. However, you can take the taxi to Tri-Cities-Regional-Airport-TRI airport, fly to Des Moines (DSM), then take the taxi to Des Moines. Alternatively, you can take a vehicle from Greeneville to Des Moines via Charlie Haun WB Aft Washington PK, Walmart, Knoxville, Nashville, Nashville Bus Station, Carbondale, St. Louis, and St Louis Bus Station in around 24h 20m.

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