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How to get fromGreensboro to Buffaloby plane, bus, train (Amtrak), car, train, or bus (Flixbus, Greyhound)

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There are 7 ways to get from Greensboro to Buffalo by plane, bus, train (Amtrak), car, train, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Piedmont Triad International Airport

    best
    1. Fly from Piedmont Triad International Airport (GSO) to Buffalo Niagara International Airport (BUF)plane plane GSO - BUF
    4h 54m
    $143–738

  2. Bus

    cheapest
    1. Take the bus from Greensboro to Winston-Salembus bus
    2. Take the bus from Winston Salem to Charlestonbus bus
    3. Take the bus from Charleston, WV to Cleveland, OHbus bus
    4. Take the bus from Cleveland, OH to Buffalo, NYbus bus
    16h 50m
    $71–199

  3. Train (Amtrak)

    1. Take the train from Greensboro to Ny Moynihan Train Hall At Penn Stationtrain train Crescent / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train Empire Service / ...
    20h 48m
    $247–560

  4. Drive  580.6 mi

    1. Drive from Greensboro to Buffalocar car 580.6 mi
    12h 1m
    $106–153

  5. Train to Raleigh-Durham International Airport, fly

    1. Take the train from Greensboro to Durham Amtrak Stationtrain train
    2. Fly from Raleigh-Durham International Airport (RDU) to Buffalo Niagara International Airport (BUF)plane plane RDU - BUF
    6h 1m
    $141–460

  6. Bus via Washington

    1. Take the bus from Greensboro Bus Stop to Washington Union Stationbus bus
    2. Take the bus from Washington Union Station to Ithacabus bus
    3. Take the bus from Ithaca to Buffalobus bus
    21h 45m
    $145–257

  7. Train, bus

    1. Take the train from Greensboro to Carytrain train
    2. Take the train from Cary to Pittsburgh Amtrak Stationtrain train
    3. Take the bus from Pittsburgh, Pa to Buffalo, Nybus bus 510
    26h 24m
    $224–593

Greensboro to Buffalo by bus

Calendar7Weekly Buses
Duration16h 50mAverage Duration
Ticket$71Cheapest Price
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Questions & Answers

Map of how to get from Greensboro to Buffalo.ExpandLaunch map view
  • Distance: 500.5 mi
  • Duration: 4h 54m

What companies run services between Greensboro, NC, USA and Buffalo, NY, USA?

United Airlines, Delta, and American Airlines fly from Piedmont Triad International Airport (GSO) to Buffalo Niagara International Airport (BUF) hourly. Alternatively, you can take a bus from Greensboro to Buffalo, NY via Winston Salem, Charleston, Charleston, WV, and Cleveland, OH in around 16h 50m.

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