There are 7 ways to get from Greensboro to Defiance by train, plane, taxi, bus, train (Amtrak), car, or bus (Greyhound, Flixbus, Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Charlotte Douglas International Airport, fly to Fort Wayne International Airport, taxi
best- Take the train from Greensboro to Charlotte Amtrak Stationtrain
- Fly from Charlotte Douglas International Airport (CLT) to Fort Wayne International Airport (FWA)plane CLT - FWA
- Take the taxi from Fort Wayne International Airport (FWA) to Defiancetaxi
6h 35m$231–620Drive 524.5 mi
cheapest- Drive from Greensboro to Defiancecar 524.5 mi
9h 47m$96–139Bus, taxi
- Take the bus from Greensboro to Winston-Salembus
- Take the bus from Winston Salem to Columbusbus
- Take the bus from Wilson & Ferrell Shell Station - Columbus to Delphosbus
- Take the taxi from Delphos to Defiancetaxi
15h 15m$142–224Train (Amtrak)
- Take the train from Greensboro to Carytrain
- Take the train from Cary to Toledotrain
- Take the train from Toledo to Bryan Amtrak Stationtrain
25h 22m$319–760Fly Piedmont Triad International Airport to Detroit, bus, train
- Fly from Piedmont Triad International Airport (GSO) to Detroit (DTW)plane GSO - DTW
- Take the bus from Dearborn to Toledobus
- Take the train from Toledo to Bryan Amtrak Stationtrain
7h 42m$218–772Train to Charlotte Douglas International Airport, fly to Dayton, drive
- Take the train from Greensboro to Charlotte Amtrak Stationtrain
- Fly from Charlotte Douglas International Airport (CLT) to Dayton (DAY)plane CLT - DAY
- Drive from Dayton-Airport-DAY to Defiancecar
7h 31m$105–449Bus
- Take the bus from Greensboro Bus Stop to Charlotte Bus Stationbus
- Take the bus from Charlotte Bus Station to Toledo Bus Stopbus
- Take the bus from Toledo to Bryan Amtrak Stationbus
18h 30m$178–274
Charlotte Douglas International Airport (CLT) to Fort Wayne International Airport (FWA) flights
Comparing Your Travel Options
The cheapest way to get from Greensboro to Defiance is to drive which costs $95 - $140 and takes 9h 47m.
The fastest way to get from Greensboro to Defiance is to train and fly and taxi which takes 6h 35m and costs $230 - $650.
No, there is no direct bus from Greensboro to Defiance station. However, there are services departing from Greensboro Bus Stop and arriving at Bryan Amtrak Station via Charlotte Bus Station and Toledo. The journey, including transfers, takes approximately 18h 30m.
No, there is no direct train from Greensboro to Defiance station. However, there are services departing from Greensboro and arriving at Bryan Amtrak Station via Cary and Toledo. The journey, including transfers, takes approximately 25h 22m.
The distance between Greensboro and Defiance is 618 miles. The road distance is 527.6 miles.
The best way to get from Greensboro to Defiance without a car is to bus and taxi which takes 15h 15m and costs $140 - $230.
It takes approximately 6h 35m to get from Greensboro to Defiance, including transfers.
Greensboro to Defiance bus services, operated by Greyhound USA, depart from Greensboro Bus Stop station.
Greensboro to Defiance train services, operated by Amtrak, depart from Greensboro station.
The best way to get from Greensboro to Defiance is to train which takes 25h 22m and costs $310 - $800. Alternatively, you can bus, which costs $170 - $280 and takes 18h 30m.
What companies run services between Greensboro, NC, USA and Defiance, OH, USA?
You can take a train from Greensboro to Defiance via Cary, Toledo, and Bryan Amtrak Station in around 25h 22m. Alternatively, you can take a bus from Greensboro Bus Stop to Defiance via Charlotte Bus Station, Toledo, and Bryan Amtrak Station in around 18h 30m.
- Website
- aa.com
Flights from Charlotte Douglas International Airport to Fort Wayne International Airport
- Ave. Duration
- 1h 55m
- When
- Every day
- Estimated price
- $60–370
Flights from Piedmont Triad International Airport to Detroit via Charlotte Douglas International Airport
- Ave. Duration
- 4h 19m
- When
- Every day
- Estimated price
- $110–650
Flights from Piedmont Triad International Airport to Detroit via Reagan Washington
- Ave. Duration
- 4h 8m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–700
Flights from Charlotte Douglas International Airport to Dayton
- Ave. Duration
- 1h 43m
- When
- Every day
- Estimated price
- $55–350
- Website
- delta.com
Flights from Charlotte Douglas International Airport to Fort Wayne International Airport via Atlanta
- Ave. Duration
- 4h
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $75–430
Flights from Piedmont Triad International Airport to Detroit
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $100–600
Flights from Piedmont Triad International Airport to Detroit via Atlanta
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $140–750
Flights from Charlotte Douglas International Airport to Dayton via Atlanta
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- $70–410
- Website
- united.com
Flights from Piedmont Triad International Airport to Detroit via Washington Dulles
- Ave. Duration
- 4h 9m
- When
- Every day
- Estimated price
- $110–650
Flights from Charlotte Douglas International Airport to Dayton via Washington Dulles
- Ave. Duration
- 3h 56m
- When
- Monday, Thursday, Friday, Sunday, and Saturday
- Estimated price
- $75–420
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Greensboro to Charlotte Amtrak Station
- Ave. Duration
- 1h 35m
- Frequency
- Every 4 hours
- Estimated price
- $25–65
- Website
- Amtrak
Train from Greensboro to Cary
- Ave. Duration
- 1h 27m
- Frequency
- 5 times a day
- Estimated price
- $19–55
- Website
- Amtrak
Train from Cary to Toledo
- Ave. Duration
- 20h 35m
- Frequency
- Once daily
- Estimated price
- $230–600
- Website
- Amtrak
Train from Toledo to Bryan Amtrak Station
- Ave. Duration
- 50 min
- Frequency
- Twice daily
- Estimated price
- $14–40
- Website
- Amtrak
Train from Toledo to Bryan Amtrak Station
- Ave. Duration
- 50 min
- Frequency
- Twice daily
- Estimated price
- $14–40
- Website
- Amtrak
Train from Greensboro to Charlotte Amtrak Station
- Ave. Duration
- 1h 35m
- Frequency
- Every 4 hours
- Estimated price
- $25–65
- Website
- Amtrak
- Phone
- +1 704-348-1200
- [email protected]
- Website
- Sunway Charters
Bus from Greensboro to Winston-Salem
- Ave. Duration
- 35 min
- Frequency
- Twice daily
- Estimated price
- $6–9
- Schedules at
- Sunway Charters
- Passenger
- $6–9
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Winston Salem to Columbus
- Ave. Duration
- 9h 40m
- Frequency
- Once daily
- Estimated price
- $40–90
- Website
- Barons Bus
- Phone
- +1 888 954 6287
- [email protected]
- Website
- Go bus
Bus from Wilson & Ferrell Shell Station - Columbus to Delphos
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $11–15
- Website
- Go bus
- Book at
- Go bus booking
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Dearborn to Toledo
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $16–24
- Website
- Amtrak
Bus from Toledo to Bryan Amtrak Station
- Ave. Duration
- 50 min
- Frequency
- Once a week
- Estimated price
- $14–21
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Greensboro Bus Stop to Charlotte Bus Station
- Ave. Duration
- 1h 30m
- Frequency
- 4 times a day
- Estimated price
- $14–23
- Website
- Greyhound
Bus from Charlotte Bus Station to Toledo Bus Stop
- Ave. Duration
- 13h 40m
- Frequency
- Once daily
- Estimated price
- $95–160
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Greensboro Bus Stop to Charlotte Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- 3 times a day
- Estimated price
- $13–21
- Schedules at
- Flixbus USA
- Ave. Duration
- 1h 2m
- Estimated price
- $85–180
Deluxe Taxi Co
- Phone
- +1-260-426-8555
- Website
- deluxetaxifortwayne.net
Black and White Transportation
- Phone
- +1-419-536-8294
- Website
- bwtransportation.com
Want to know more about travelling around United States
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Booking & Getting There
Greensboro to Defiance bus services, operated by Greyhound USA, arrive at Charlotte Bus Station.
Greensboro to Defiance train services, operated by Amtrak, arrive at Cary station.
Yes, the driving distance between Greensboro to Defiance is 528 miles. It takes approximately 9h 47m to drive from Greensboro to Defiance.
There are 13+ hotels available in Defiance.















