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How to get fromGreensboro to Des Moinesby plane, bus (Greyhound), train, bus, or car

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There are 8 ways to get from Greensboro to Des Moines by plane, bus (Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Piedmont Triad International Airport

    best
    1. Fly from Piedmont Triad International Airport (GSO) to Des Moines (DSM)plane plane GSO - DSM
    4h 51m
    $238–1,007

  2. Bus

    cheapest
    1. Take the bus from Greensboro Bus Stop to Winston Salem(Trans Center)bus bus
    2. Take the bus from Winston Salem(Trans Center) to Columbus - Mound Stbus bus
    3. Take the bus from Columbus to Indianapolis Union Stationbus bus
    4. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    26h 55m
    $138–293

  3. Train, bus

    1. Take the train from Greensboro to Charlottesvilletrain train
    2. Take the train from Charlottesville to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    30h 43m
    $316–652

  4. Drive 1,000.6 mi

    1. Drive from Greensboro to Des Moinescar car 1,000.6 mi
    17h 24m
    $183–264

  5. Train to Charlotte Douglas International Airport, fly

    1. Take the train from Greensboro to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Des Moines (DSM)plane plane CLT - DSM
    6h 20m
    $223–937

  6. Bus via Lewisville

    1. Take the bus from Greensboro to Winston-Salembus bus
    2. Take the bus from Winston Salem to Columbusbus bus
    3. Take the bus from Columbus to Indianapolisbus bus
    4. Take the bus from Indianapolis to Des Moinesbus bus
    28h 59m

  7. Train, bus via Chicago

    1. Take the train from Greensboro to Carytrain train
    2. Take the train from Cary to Chicago Union Stationtrain train
    3. Take the bus from Chicago to Des Moinesbus bus
    35h 58m

  8. Train, bus via Galesburg

    1. Take the train from Greensboro to Raleigh Union Stationtrain train
    2. Take the train from Raleigh Union Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    4. Take the bus from Galesburg to Des Moinesbus bus
    36h 41m
    $446–927

Greensboro to Des Moines by bus

Calendar7Weekly Buses
Duration26h 55mAverage Duration
Ticket$138Cheapest Price
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Questions & Answers

Map of how to get from Greensboro to Des Moines.ExpandLaunch map view
  • Distance: 845.1 mi
  • Duration: 4h 51m

What companies run services between Greensboro, NC, USA and Des Moines, IA, USA?

American Airlines, United Airlines, and two other airlines fly from Piedmont Triad International Airport (GSO) to Des Moines (DSM) hourly. Alternatively, you can take a bus from Greensboro Bus Stop to Des Moines via Winston Salem(Trans Center), Columbus, and Indianapolis Union Station in around 26h 55m.

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