There are 7 ways to get from Greensboro to Des Moines by plane, bus (Greyhound), train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Piedmont Triad International Airport
best- Fly from Piedmont Triad International Airport (GSO) to Des Moines (DSM)plane GSO - DSM
5h$149–609Bus
- Take the bus from Greensboro to Winston-Salembus
- Take the bus from Winston Salem to Columbusbus
- Take the bus from Columbus to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to Des Moinesbus
26h 55m$156–279Train, bus
- Take the train from Greensboro to Charlottesvilletrain
- Take the train from Charlottesville to Indianapolistrain
- Take the bus from Indianapolis Union Station to Des Moinesbus
30h 38m$505–826Drive 1,000.6 mi
- Drive from Greensboro to Des Moinescar 1,000.6 mi
17h 24m$183–264Train to Charlotte Douglas International Airport, fly
- Take the train from Greensboro to Charlotte Amtrak Stationtrain
- Fly from Charlotte Douglas International Airport (CLT) to Des Moines (DSM)plane CLT - DSM
6h 19m$160–557Train, bus via Chicago
- Take the train from Greensboro to Carytrain
- Take the train from Cary to Chicago Union Stationtrain
- Take the bus from Chicago Bus Station to Des Moinesbus
35h 18m$650–1,101Train, bus via Galesburg
- Take the train from Greensboro to Raleigh Union Stationtrain
- Take the train from Raleigh Union Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain
- Take the bus from Galesburg to Des Moinesbus
36h 41m$715–1,213
Greensboro to Des Moines by bus
Comparing Your Travel Options
The cheapest way to get from Greensboro to Des Moines is to bus which costs $150 - $280 and takes 26h 55m.
The fastest way to get from Greensboro to Des Moines is to fly which takes 5h and costs $140 - $650.
No, there is no direct bus from Greensboro to Des Moines. However, there are services departing from Greensboro and arriving at Des Moines via Winston Salem, Columbus and Indianapolis Union Station. The journey, including transfers, takes approximately 26h 55m.
The distance between Greensboro and Des Moines is 850 miles. The road distance is 1006.5 miles.
The best way to get from Greensboro to Des Moines without a car is to bus which takes 26h 55m and costs $150 - $280.
It takes approximately 5h to get from Greensboro to Des Moines, including transfers.
Greensboro to Des Moines bus services, operated by Sunway Charters, depart from Greensboro station.
The best way to get from Greensboro to Des Moines is to fly which takes 5h and costs $140 - $650. Alternatively, you can bus, which costs $150 - $280 and takes 26h 55m.
Greensboro to Des Moines bus services, operated by Sunway Charters, arrive at Winston-Salem station.
Des Moines is 1h behind Greensboro. It is currently 4:39 PM in Greensboro and 3:39 PM in Des Moines.
What companies run services between Greensboro, NC, USA and Des Moines, IA, USA?
American Airlines, Delta, and United Airlines fly from Piedmont Triad International Airport (GSO) to Des Moines (DSM) every 2 hours. Alternatively, you can take a bus from Greensboro to Des Moines via Winston Salem, Columbus, and Indianapolis Union Station in around 26h 55m.
- Website
- aa.com
Flights from Piedmont Triad International Airport to Des Moines via Charlotte Douglas International Airport
- Ave. Duration
- 5h 14m
- When
- Sunday, Tuesday, Wednesday, Saturday, and Thursday
- Estimated price
- $100–550
Flights from Piedmont Triad International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 6h 52m
- When
- Every day
- Estimated price
- $100–550
Flights from Piedmont Triad International Airport to Des Moines via Philadelphia
- Ave. Duration
- 5h 39m
- When
- Monday, Thursday, Friday, Sunday, Tuesday, and Wednesday
- Estimated price
- $130–650
Flights from Charlotte Douglas International Airport to Des Moines
- Ave. Duration
- 2h 33m
- When
- Every day
- Estimated price
- $85–450
Flights from Charlotte Douglas International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- $90–470
- Website
- delta.com
Flights from Piedmont Triad International Airport to Des Moines via Detroit
- Ave. Duration
- 4h 42m
- When
- Every day
- Estimated price
- $110–600
Flights from Piedmont Triad International Airport to Des Moines via Atlanta
- Ave. Duration
- 5h 28m
- When
- Every day
- Estimated price
- $110–600
Flights from Charlotte Douglas International Airport to Des Moines via Detroit
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $100–500
Flights from Charlotte Douglas International Airport to Des Moines via Atlanta
- Ave. Duration
- 4h 46m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $95–480
- Website
- united.com
Flights from Piedmont Triad International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 57m
- When
- Every day
- Estimated price
- $100–550
Flights from Charlotte Douglas International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 46m
- When
- Every day
- Estimated price
- $90–470
- Website
- southwest.com
Flights from Charlotte Douglas International Airport to Des Moines via Nashville
- Ave. Duration
- 4h 15m
- When
- Tuesday and Wednesday
- Estimated price
- $85–460
Flights from Charlotte Douglas International Airport to Des Moines via Chicago Midway
- Ave. Duration
- 4h 33m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $90–470
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Greensboro to Charlottesville
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- $95–150
- Website
- Amtrak
Train from Charlottesville to Indianapolis
- Ave. Duration
- 15h 23m
- Frequency
- 3 times a week
- Estimated price
- $330–550
- Website
- Amtrak
Train from Greensboro to Charlotte Amtrak Station
- Ave. Duration
- 1h 35m
- Frequency
- Every 4 hours
- Estimated price
- $50–80
- Website
- Amtrak
Train from Greensboro to Cary
- Ave. Duration
- 1h 27m
- Frequency
- 5 times a day
- Estimated price
- $40–65
- Website
- Amtrak
Train from Cary to Chicago Union Station
- Ave. Duration
- 25h 12m
- Frequency
- Once daily
- Estimated price
- $550–950
- Website
- Amtrak
Train from Greensboro to Raleigh Union Station
- Ave. Duration
- 1h 42m
- Frequency
- 5 times a day
- Estimated price
- $40–70
- Website
- Amtrak
Train from Raleigh Union Station to Chicago Union Station
- Ave. Duration
- 24h 28m
- Frequency
- Once daily
- Estimated price
- $550–950
- Website
- Amtrak
Train from Chicago Union Station to Galesburg Amtrak Station
- Ave. Duration
- 2h 36m
- Frequency
- 4 times a day
- Estimated price
- $85–140
- Website
- Amtrak
- Phone
- +1 704-348-1200
- [email protected]
- Website
- Sunway Charters
Bus from Greensboro to Winston-Salem
- Ave. Duration
- 35 min
- Frequency
- Twice daily
- Estimated price
- $6–9
- Schedules at
- Sunway Charters
- Passenger
- $6–9
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Winston Salem to Columbus
- Ave. Duration
- 9h 20m
- Frequency
- Once daily
- Estimated price
- $40–90
- Website
- Barons Bus
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Columbus to Indianapolis Union Station
- Ave. Duration
- 4h 10m
- Frequency
- 3 times a day
- Estimated price
- $30–50
- Website
- Greyhound
Bus from Indianapolis Union Station to Des Moines
- Ave. Duration
- 9h 50m
- Frequency
- Once daily
- Estimated price
- $80–130
- Website
- Greyhound
Bus from Indianapolis Union Station to Des Moines
- Ave. Duration
- 9h 50m
- Frequency
- Once daily
- Estimated price
- $80–130
- Website
- Greyhound
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a day
- Estimated price
- $60–90
- Website
- Greyhound
Bus from Galesburg to Des Moines
- Ave. Duration
- 4h 55m
- Frequency
- Once daily
- Estimated price
- $35–55
- Website
- Greyhound
Want to know more about travelling around United States
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Booking & Getting There
Yes, the driving distance between Greensboro to Des Moines is 1006 miles. It takes approximately 17h 24m to drive from Greensboro to Des Moines.
Book your Greensboro to Des Moines bus tickets online with Omio.
There are 190+ hotels available in Des Moines.











