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How to get fromGreensboro to Louisvilleby plane, bus (Greyhound), train, bus, car, or bus (Flixbus, Greyhound, Amtrak)

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There are 7 ways to get from Greensboro to Louisville by plane, bus (Greyhound), train, bus, car, or bus (Flixbus, Greyhound, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Piedmont Triad International Airport

    best
    1. Fly from Piedmont Triad International Airport (GSO) to Louisville International Airport (SDF)plane plane GSO - SDF
    4h 50m
    $142–689

  2. Bus via Columbus

    cheapest
    1. Take the bus from Greensboro Bus Stop to Winston Salem(Trans Center)bus bus
    2. Take the bus from Winston Salem(Trans Center) to Columbus - Mound Stbus bus
    3. Take the bus from Columbus - Downtown - Mound St to Louisville, KY Bus Stationbus bus
    16h 25m
    $60–158

  3. Train, bus (Amtrak)

    1. Take the train from Greensboro to Charlottesvilletrain train
    2. Take the train from Charlottesville to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    23h 13m
    $268–558

  4. Drive 445 mi

    1. Drive from Greensboro to Louisvillecar car 445 mi
    8h 34m
    $82–118

  5. Train to Raleigh-Durham International Airport, fly

    1. Take the train from Greensboro to Durham Amtrak Stationtrain train
    2. Fly from Raleigh-Durham International Airport (RDU) to Louisville International Airport (SDF)plane plane RDU - SDF
    6h 11m
    $118–595

  6. Train to Charlotte Douglas International Airport, fly

    1. Take the train from Greensboro to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Louisville International Airport (SDF)plane plane CLT - SDF
    6h 21m
    $127–670

  7. Bus

    1. Take the bus from Greensboro Bus Stop to Lynchburg Transit Centerbus bus
    2. Take the bus from Lynchburg Transit Center to Nashville Bus Stationbus bus
    3. Take the bus from Nashville to Louisville, KYbus bus
    19h 20m
    $125–241

Greensboro to Louisville by bus

Calendar7Weekly Buses
Duration16h 25mAverage Duration
Ticket$60Cheapest Price
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Questions & Answers

Map of how to get from Greensboro to Louisville.ExpandLaunch map view
  • Distance: 368.5 mi
  • Duration: 4h 50m

What companies run services between Greensboro, NC, USA and Louisville, KY, USA?

American Airlines, Delta, and two other airlines fly from Piedmont Triad International Airport (GSO) to Louisville International Airport (SDF) hourly. Alternatively, you can take a bus from Greensboro Bus Stop to Louisville, KY Bus Station via Winston Salem(Trans Center) and Columbus - Downtown - Mound St in around 16h 25m.

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