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How to get fromGreensboro to Santeeby bus (Greyhound, Flixbus), train, car, or plane

Find Transport to Santee

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There are 5 ways to get from Greensboro to Santee by bus (Greyhound, Flixbus), train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Greensboro Bus Stop to Charlotte Bus Stationbus bus Greyhound US0670
    2. Take the bus from Charlotte Bus Station to Orangeburgbus bus Greyhound US0644S / ...
    7h 8m
    $119–176

  2. Drive 206.1 mi

    cheapest
    1. Drive from Greensboro to Santeecar car 206.1 mi
    3h 49m
    $38–55

  3. Train, drive (Amtrak)

    1. Take the train from Greensboro to Selma Stationtrain train
    2. Take the train from Selma Station to Charleston Amtrak Stationtrain train
    3. Drive from Charleston Amtrak Station to Santeecar car
    8h 41m
    $115–238

  4. Fly from Piedmont Triad International Airport, drive

    1. Fly from Piedmont Triad International Airport (GSO) to Columbia (CAE)plane plane GSO - CAE
    2. Drive from Columbia-Airport-CAE to Santeecar car
    4h 23m
    $171–1,002

  5. Train to Charlotte Douglas International Airport, fly, drive

    1. Take the train from Greensboro to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Columbia (CAE)plane plane CLT - CAE
    3. Drive from Columbia-Airport-CAE to Santeecar car
    5h 49m
    $145–933

Piedmont Triad International Airport (GSO) to Columbia (CAE) flights

Calendar116Weekly Planes
Duration4h 24mAverage Duration
Ticket$134Cheapest Price
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Questions & Answers

Map of how to get from Greensboro to Santee.ExpandLaunch map view
  • Distance: 280.1 mi
  • Duration: 7h 8m

What companies run services between Greensboro, NC, USA and Santee, SC, USA?

You can take a bus from Greensboro Bus Stop to Santee via Charlotte Bus Station and Orangeburg in around 7h 8m.

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