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How to get fromGreensburg to St. Louisby train, bus, plane, bus (Greyhound), train (Amtrak), or car

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There are 4 ways to get from Greensburg to St. Louis by train, bus, plane, bus (Greyhound), train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus, fly

    best
    1. Take the train from Greensburg Amtrak to Pittsburgh Amtrak Stationtrain train
    2. Take the bus from Liberty Ave + Tito Way to Pittsburgh International Airportbus bus
    3. Fly from Pittsburgh International Airport (PIT) to Lambert–St. Louis International Airport (STL)plane plane PIT - STL
    5h 56m

  2. Bus

    cheapest
    1. Take the bus from WCTA Transit Center to East Buswaybus bus 1F / ...
    2. Take the bus from Pittsburgh Intermodal Station to St Louis Bus Stationbus bus Greyhound US0421
    15h 24m
    $95–189

  3. Train (Amtrak)

    1. Take the train from Greensburg Amtrak to Pittsburgh Amtrak Stationtrain train
    2. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Louistrain train
    17h 29m
    $235–530

  4. Drive 619.7 mi

    1. Drive from Greensburg to St. Louiscar car 619.7 mi
    10h 37m
    $114–164

Greensburg to St. Louis by bus

Calendar21Weekly Buses
Duration15h 24mAverage Duration
Ticket$95Cheapest Price
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Questions & Answers

Map of how to get from Greensburg to St. Louis.ExpandLaunch map view
  • Distance: 621.4 mi
  • Duration: 5h 56m

What companies run services between Greensburg, PA, USA and St. Louis, MO, USA?

You can take a bus from WCTA Transit Center to St Louis Bus Station via East Busway and Pittsburgh Intermodal Station in around 15h 24m. Alternatively, you can take a train from Greensburg Amtrak to St. Louis via Pittsburgh Amtrak Station and Chicago Union Station in around 17h 29m.

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