Rome2Rio

How to get fromGreenville to Destinby car, plane, train, bus, or taxi

Find Transport to Destin

See all options

There are 7 ways to get from Greenville to Destin by car, plane, train, bus, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Bill And Hillary Clinton National Airport, fly to Destin–Fort Walton Beach Airport

    best
    1. Drive from Greenville to Bill And Hillary Clinton National Airport (LIT)car car
    2. Fly from Bill And Hillary Clinton National Airport (LIT) to Destin–Fort Walton Beach Airport (VPS)plane plane LIT - VPS
    7h 18m
    $177–694

  2. Drive 406.4 mi

    cheapest
    1. Drive from Greenville to Destincar car 406.4 mi
    7h 48m
    $75–108

  3. Drive, train, bus, taxi

    1. Drive from Greenville to Yazoo City Amtrak Stationcar car
    2. Take the train from Yazoo City Amtrak Station to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain train
    4. Take the bus from Gulfport to Crestviewbus bus
    5. Take the taxi from Crestview to Destintaxi taxi
    13h 24m
    $240–390

  4. Drive, train, bus, taxi via Jackson

    1. Drive from Greenville to Yazoo City Amtrak Stationcar car
    2. Take the train from Yazoo City Amtrak Station to Jacksontrain train
    3. Take the bus from Jackson to New Orleans Bus Stationbus bus
    4. Take the bus from New Orleans Bus Station to Biloxi Transit Centerbus bus
    5. Take the bus from Biloxi to Crestviewbus bus
    6. Take the taxi from Crestview to Destintaxi taxi
    15h 19m
    $206–311

  5. Fly Greenville International Airport to Destin–Fort Walton Beach Airport

    1. Fly from Greenville International Airport (GLH) to Destin–Fort Walton Beach Airport (VPS)plane plane GLH - VPS
    6h
    $157–531

  6. Fly Greenville International Airport to Northwest Florida Beaches International Airport, taxi

    1. Fly from Greenville International Airport (GLH) to Northwest Florida Beaches International Airport (ECP)plane plane GLH - ECP
    2. Take the taxi from Northwest Florida Beaches International Airport (ECP) to Destintaxi taxi
    6h 4m
    $257–666

  7. Fly Greenville International Airport to Pensacola International Airport, taxi

    1. Fly from Greenville International Airport (GLH) to Pensacola International Airport (PNS)plane plane GLH - PNS
    2. Take the taxi from Pensacola-Airport-PNS to Destintaxi taxi
    5h 18m
    $222–576

Bill And Hillary Clinton National Airport (LIT) to Destin–Fort Walton Beach Airport (VPS) flights

Calendar44Weekly Planes
Duration5h 21mAverage Duration
Ticket$115Cheapest Price
See schedules

Questions & Answers

Map of how to get from Greenville to Destin.ExpandLaunch map view
  • Distance: 604.2 mi
  • Duration: 7h 18m

What companies run services between Greenville, MS, USA and Destin, FL, USA?

Key Lime, Delta, and American Airlines fly from Greenville International Airport (GLH) to Destin–Fort Walton Beach Airport (VPS) twice daily.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound