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How to get fromGreenville to Chicagoby bus, plane, bus (Greyhound, Flixbus), train, or car

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There are 8 ways to get from Greenville to Chicago by bus, plane, bus (Greyhound, Flixbus), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Norfolk International Airport, fly to Chicago Midway International Airport

    best
    1. Take the bus from Greenville GK Butterfield Trans Ctr to Norfolkbus bus
    2. Fly from Norfolk International Airport (ORF) to Chicago Midway International Airport (MDW)plane plane ORF - MDW
    6h 54m
    $115–476

  2. Fly Greenville to Chicago Midway International Airport

    cheapest
    1. Fly from Greenville (PGV) to Chicago Midway International Airport (MDW)plane plane PGV - MDW
    5h 22m
    $85–415

  3. Bus

    1. Take the bus from Greenville GK Butterfield Trans Ctr to Raleigh Bus Stationbus bus
    2. Take the bus from Raleigh Bus Station to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Chicago Bus Stationbus bus
    25h 30m
    $147–307

  4. Bus, train

    1. Take the bus from Greenville GK Butterfield Trans Ctr to Raleigh Bus Stationbus bus Greyhound US0652s / ...
    2. Take the train from Raleigh Union Station to Chicago Union Stationtrain train Floridian
    27h 45m
    $344–724

  5. Drive 864.6 mi

    1. Drive from Greenville to Chicagocar car 864.6 mi
    15h 16m
    $158–228

  6. Bus to Wilmington International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Greenville GK Butterfield Trans Ctr to Wilmington Cape Fear Public Transitbus bus
    2. Fly from Wilmington International Airport (ILM) to Chicago O'Hare International Airport (ORD)plane plane ILM - ORD
    7h 52m
    $97–383

  7. Bus to Raleigh-Durham International Airport, fly to Chicago Midway International Airport

    1. Take the bus from Greenville GK Butterfield Trans Ctr to Raleigh Bus Stationbus bus
    2. Fly from Raleigh-Durham International Airport (RDU) to Chicago Midway International Airport (MDW)plane plane RDU - MDW
    7h 19m
    $169–332

  8. Bus to Raleigh-Durham International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Greenville GK Butterfield Trans Ctr to Raleigh Bus Stationbus bus
    2. Fly from Raleigh-Durham International Airport (RDU) to Chicago O'Hare International Airport (ORD)plane plane RDU - ORD
    7h 57m
    $189–782

Greenville to Chicago by bus

Calendar14Weekly Buses
Duration25h 30mAverage Duration
Ticket$147Cheapest Price
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Questions & Answers

Map of how to get from Greenville to Chicago.ExpandLaunch map view
  • Distance: 857.5 mi
  • Duration: 6h 54m

What companies run services between Greenville, Pitt County, NC, USA and Chicago, IL, USA?

You can take a bus from Greenville GK Butterfield Trans Ctr to Chicago Bus Station via Raleigh Bus Station and Washington Union Station in around 25h 30m. Alternatively, American Airlines and Southwest Airlines fly from Greenville (PGV) to Chicago Midway International Airport (MDW) once daily.

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