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How to get fromGreenville to Cape Girardeauby plane, bus, taxi, car, or bus (Greyhound)

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There are 7 ways to get from Greenville to Cape Girardeau by plane, bus, taxi, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Lambert–St. Louis International Airport, bus

    best
    1. Fly from Greenville–Spartanburg International Airport (GSP) to Lambert–St. Louis International Airport (STL)plane plane GSP - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    7h 25m
    $178–745

  2. Drive 543.1 mi

    cheapest
    1. Drive from Greenville to Cape Girardeaucar car 543.1 mi
    9h 46m
    $100–144

  3. Bus, taxi

    1. Take the bus from Taqueria Guadalajara - Greenville to Atlantabus bus
    2. Take the bus from Atlanta Bus Station to Carbondale Intermodal Stationbus bus
    3. Take the taxi from Carbondale Intermodal Station to Cape Girardeautaxi taxi
    14h 37m
    $228–421

  4. Fly to Williamson County Regional Airport, taxi

    1. Fly from Greenville–Spartanburg International Airport (GSP) to Williamson County Regional Airport (MWA)plane plane GSP - MWA
    2. Take the taxi from Williamson County Regional Airport (MWA) to Cape Girardeautaxi taxi
    8h 24m
    $281–758

  5. Fly to Nashville, bus, taxi

    1. Fly from Greenville–Spartanburg International Airport (GSP) to Nashville (BNA)plane plane GSP - BNA
    2. Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus bus
    3. Take the taxi from Carbondale Intermodal Station to Cape Girardeautaxi taxi
    8h 2m
    $233–655

  6. Fly to Cape Girardeau Municipal Airport

    1. Fly from Greenville–Spartanburg International Airport (GSP) to Cape Girardeau Municipal Airport (CGI)plane plane GSP - CGI
    7h 40m
    $174–676

  7. Bus

    1. Take the bus from Taqueria Guadalajara - Greenville to Atlantabus bus
    2. Take the bus from Atlanta Bus Station to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Cape Girardeaubus bus
    17h 30m
    $151–345

Greenville–Spartanburg International Airport (GSP) to Lambert–St. Louis International Airport (STL) flights

Calendar117Weekly Planes
Duration4h 58mAverage Duration
Ticket$114Cheapest Price
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Questions & Answers

Map of how to get from Greenville to Cape Girardeau.ExpandLaunch map view
  • Distance: 666.5 mi
  • Duration: 7h 25m

What companies run services between Greenville, SC, USA and Cape Girardeau, MO, USA?

American Airlines, Corporate Flight Management Inc, and three other airlines fly from Greenville–Spartanburg International Airport (GSP) to Cape Girardeau Municipal Airport (CGI) 4 times a day. Alternatively, you can take a vehicle from Greenville to Cape Girardeau via Taqueria Guadalajara - Greenville, Atlanta, Doraville Station, Garnett Station, Atlanta Bus Station, Memphis Bus Station, and Cape Girardeau in around 17h 30m.

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