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How to get fromGreenville to Clevelandby plane, bus (Greyhound), bus, train, car, or taxi

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There are 6 ways to get from Greenville to Cleveland by plane, bus (Greyhound), bus, train, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Greenville–Spartanburg International Airport

    best
    1. Fly from Greenville–Spartanburg International Airport (GSP) to Cleveland-Hopkins International Airport (CLE)plane plane GSP - CLE
    4h 30m
    $144–651

  2. Drive 580.2 mi

    cheapest
    1. Drive from Greenville to Clevelandcar car 580.2 mi
    10h 38m
    $106–153

  3. Bus via Charleston

    1. Take the bus from Taqueria Guadalajara - Greenville to Charlottebus bus
    2. Take the bus from Charlotte Bus Station to Charleston, WVbus bus
    3. Take the bus from Charleston, WV to Cleveland, OHbus bus
    16h 51m
    $123–319

  4. Bus, train

    1. Take the bus from Taqueria Guadalajara - Greenville to Charlottebus bus
    2. Take the train from Charlotte Amtrak Station to Carytrain train
    3. Take the train from Cary to Cleveland Amtraktrain train
    26h 40m
    $348–761

  5. Taxi to Asheville Regional Airport, fly

    1. Take the taxi from Greenville to Asheville-Airport-AVLtaxi taxi
    2. Fly from Asheville Regional Airport (AVL) to Cleveland-Hopkins International Airport (CLE)plane plane AVL - CLE
    5h 13m
    $226–647

  6. Bus

    1. Take the bus from Taqueria Guadalajara - Greenville to Atlantabus bus Charlotte
    2. Take the bus from Atlanta Bus Station to Cleveland Bus Stationbus bus Greyhound US0105
    24h 21m
    $186–414

Greenville–Spartanburg International Airport (GSP) to Cleveland-Hopkins International Airport (CLE) flights

Calendar128Weekly Planes
Duration4h 13mAverage Duration
Ticket$106Cheapest Price
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Questions & Answers

Map of how to get from Greenville to Cleveland.ExpandLaunch map view
  • Distance: 476.1 mi
  • Duration: 4h 30m

What companies run services between Greenville, SC, USA and Cleveland, OH, USA?

Southwest Airlines, Delta, and two other airlines fly from Greenville–Spartanburg International Airport (GSP) to Cleveland-Hopkins International Airport (CLE) hourly. Alternatively, you can take a vehicle from Greenville to Cleveland, OH via Taqueria Guadalajara - Greenville, Charlotte, Tryon St & Mellow Dr, Transit Center- Bay A, Transit Center- Bay E, 4th St & Graham St, Charlotte Bus Station, and Charleston, WV in around 16h 51m.

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