Rome2Rio

How to get fromGreenville to Destinby plane, bus, taxi, or car

Find Transport to Destin

See all options

There are 5 ways to get from Greenville to Destin by plane, bus, taxi, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Greenville–Spartanburg International Airport

    best
    1. Fly from Greenville–Spartanburg International Airport (GSP) to Destin–Fort Walton Beach Airport (VPS)plane plane GSP - VPS
    4h 10m
    $146–503

  2. Drive 447.5 mi

    cheapest
    1. Drive from Greenville to Destincar car 447.5 mi
    8h 55m
    $82–118

  3. Bus, taxi

    1. Take the bus from Taqueria Guadalajara - Greenville to Atlantabus bus
    2. Take the bus from Atlanta to Mobilebus bus
    3. Take the bus from Loxley to Crestviewbus bus
    4. Take the taxi from Crestview to Destintaxi taxi
    12h 45m
    $258–426

  4. Taxi to Asheville Regional Airport, fly

    1. Take the taxi from Greenville to Asheville-Airport-AVLtaxi taxi
    2. Fly from Asheville Regional Airport (AVL) to Destin–Fort Walton Beach Airport (VPS)plane plane AVL - VPS
    4h 31m
    $233–549

  5. Bus, taxi via Mobile

    1. Take the bus from Taqueria Guadalajara - Greenville to Atlantabus bus
    2. Take the bus from Atlanta Bus Station to Mobile Bus Stationbus bus
    3. Take the bus from Mobile to Crestviewbus bus
    4. Take the taxi from Crestview to Destintaxi taxi
    16h 10m
    $238–436

Greenville–Spartanburg International Airport (GSP) to Destin–Fort Walton Beach Airport (VPS) flights

Calendar65Weekly Planes
Duration4h 20mAverage Duration
Ticket$68Cheapest Price
See schedules

Questions & Answers

Map of how to get from Greenville to Destin.ExpandLaunch map view
  • Distance: 424.3 mi
  • Duration: 4h 10m

What companies run services between Greenville, SC, USA and Destin, FL, USA?

Delta, Southwest Airlines, and American Airlines fly from Greenville–Spartanburg International Airport (GSP) to Destin–Fort Walton Beach Airport (VPS) every 3 hours.

Airlines
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound