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How to get fromGreenville to Frederickby plane, bus, bus (Greyhound, Flixbus), train, car, or taxi

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There are 8 ways to get from Greenville to Frederick by plane, bus, bus (Greyhound, Flixbus), train, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Greenville–Spartanburg International Airport to Baltimore-Washington International Airport, bus

    best
    1. Fly from Greenville–Spartanburg International Airport (GSP) to Baltimore-Washington International Airport (BWI)plane plane GSP - BWI
    2. Take the bus from Baltimore Airport to Frederick Bus Stationbus bus
    3h 58m
    $196–628

  2. Drive 480.9 mi

    cheapest
    1. Drive from Greenville to Frederickcar car 480.9 mi
    9h 10m
    $88–127

  3. Bus

    1. Take the bus from Taqueria Guadalajara - Greenville to Charlottebus bus
    2. Take the bus from Charlotte Bus Station to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Frederick Bus Stationbus bus
    14h 16m
    $123–297

  4. Bus, train

    1. Take the bus from Taqueria Guadalajara - Greenville to Charlottebus bus
    2. Take the train from Charlotte Amtrak Station to Washington Union Stationtrain train
    3. Take the train from Washington Union Station to FREDERICK MARC wbtrain train
    15h 14m
    $180–423

  5. Fly Greenville–Spartanburg International Airport to Ronald Reagan Washington National Airport, bus

    1. Fly from Greenville–Spartanburg International Airport (GSP) to Ronald Reagan Washington National Airport (DCA)plane plane GSP - DCA
    2. Take the bus from SHADY GROVE & station to Frederick Marc Stationbus bus
    4h 48m
    $147–707

  6. Fly Greenville–Spartanburg International Airport to Washington Dulles International Airport, bus

    1. Fly from Greenville–Spartanburg International Airport (GSP) to Washington Dulles International Airport (IAD)plane plane GSP - IAD
    2. Take the bus from Market St & Harrison St to Frederick Transit Stationbus bus
    4h 53m
    $110–473

  7. Taxi to Asheville Regional Airport, fly to Ronald Reagan Washington National Airport, bus

    1. Take the taxi from Greenville to Asheville-Airport-AVLtaxi taxi
    2. Fly from Asheville Regional Airport (AVL) to Ronald Reagan Washington National Airport (DCA)plane plane AVL - DCA
    3. Take the bus from SHADY GROVE & station to Frederick Marc Stationbus bus
    5h 21m
    $224–663

  8. Bus, train via Lynchburg

    1. Take the bus from Taqueria Guadalajara - Greenville to Charlottebus bus
    2. Take the train from Charlotte Amtrak Station to Lynchburgtrain train
    3. Take the bus from Lynchburg Amtrak Station to Washington Union Stationbus bus
    4. Take the train from Washington Union Station to FREDERICK MARC wbtrain train
    16h 34m
    $154–368

Greenville–Spartanburg International Airport (GSP) to Baltimore-Washington International Airport (BWI) flights

Calendar14Weekly Planes
Duration1h 26mAverage Duration
Ticket$84Cheapest Price
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Questions & Answers

Map of how to get from Greenville to Frederick.ExpandLaunch map view
  • Distance: 489.6 mi
  • Duration: 3h 58m

What companies run services between Greenville, SC, USA and Frederick, MD, USA?

You can take a vehicle from Greenville to Frederick Bus Station via Taqueria Guadalajara - Greenville, Charlotte, Tryon St & Mellow Dr, Transit Center- Bay A, Transit Center- Bay E, 4th St & Graham St, Charlotte Bus Station, and Washington Union Station in around 14h 16m.

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