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How to get fromGreenville to Gainesvilleby plane, bus (Flixbus), car, taxi, or bus (Greyhound)

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There are 6 ways to get from Greenville to Gainesville by plane, bus (Flixbus), car, taxi, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Greenville–Spartanburg International Airport to Gainesville Regional Airport

    best
    1. Fly from Greenville–Spartanburg International Airport (GSP) to Gainesville Regional Airport (GNV)plane plane GSP - GNV
    5h 4m
    $113–470

  2. Drive 406.6 mi

    cheapest
    1. Drive from Greenville to Gainesvillecar car 406.6 mi
    8h 49m
    $75–108

  3. Bus

    1. Take the bus from Taqueria Guadalajara - Greenville to Atlantabus bus Charlotte
    2. Take the bus from Atlanta Bus Station to Gainesvillebus bus FlixBus N2401 / ...
    10h 25m
    $113–261

  4. Taxi to Asheville Regional Airport, fly to Gainesville Regional Airport

    1. Take the taxi from Greenville to Asheville-Airport-AVLtaxi taxi
    2. Fly from Asheville Regional Airport (AVL) to Gainesville Regional Airport (GNV)plane plane AVL - GNV
    5h 57m
    $195–506

  5. Taxi to Asheville Regional Airport, fly to Orlando Sanford, drive

    1. Take the taxi from Greenville to Asheville-Airport-AVLtaxi taxi
    2. Fly from Asheville Regional Airport (AVL) to Orlando Sanford (SFB)plane plane AVL - SFB
    3. Drive from Orlando-Sanford-Airport-SFB to Gainesvillecar car
    4h 55m
    $213–534

  6. Bus via North Walmart Supercenter

    1. Take the bus from Taqueria Guadalajara - Greenville to Atlantabus bus Charlotte
    2. Take the bus from Atlanta Bus Station to Gainesville Bus Stopbus bus Greyhound US0630
    13h 23m
    $115–268

Greenville–Spartanburg International Airport (GSP) to Gainesville Regional Airport (GNV) flights

Calendar58Weekly Planes
Duration4h 5mAverage Duration
Ticket$72Cheapest Price
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Questions & Answers

Map of how to get from Greenville to Gainesville.ExpandLaunch map view
  • Distance: 380.6 mi
  • Duration: 5h 4m

What companies run services between Greenville, SC, USA and Gainesville, FL, USA?

Delta and American Airlines fly from Greenville–Spartanburg International Airport (GSP) to Gainesville Regional Airport (GNV) every 4 hours. Alternatively, you can take a vehicle from Greenville to Gainesville via Taqueria Guadalajara - Greenville, Atlanta, Doraville Station, Garnett Station, and Atlanta Bus Station in around 10h 25m.

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