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How to get fromGreenville to Indianaby plane, train, bus (Flixbus), car, taxi, bus, or bus (Greyhound)

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There are 7 ways to get from Greenville to Indiana by plane, train, bus (Flixbus), car, taxi, bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Greenville–Spartanburg International Airport to Chicago O'Hare International Airport, train

    best
    1. Fly from Greenville–Spartanburg International Airport (GSP) to Chicago O'Hare International Airport (ORD)plane plane GSP - ORD
    2. Take the train from Van Buren St. to Gary Metro Centertrain train
    4h 31m
    $115–432

  2. Drive 489.2 mi

    cheapest
    1. Drive from Greenville to Indianapoliscar car 489.2 mi
    9h 32m
    $90–129

  3. Bus

    1. Take the bus from Taqueria Guadalajara - Greenville to Atlantabus bus Charlotte
    2. Take the bus from Atlanta Bus Station to Indianapolisbus bus FlixBus 2512
    16h 55m
    $153–331

  4. Taxi to Asheville Regional Airport, fly to Chicago O'Hare International Airport, train

    1. Take the taxi from Greenville to Asheville-Airport-AVLtaxi taxi
    2. Fly from Asheville Regional Airport (AVL) to Chicago O'Hare International Airport (ORD)plane plane AVL - ORD
    3. Take the train from Van Buren St. to Gary Metro Centertrain train
    5h 8m
    $197–468

  5. Bus to Charlotte Douglas International Airport, fly to Evansville

    1. Take the bus from Taqueria Guadalajara - Greenville to Charlottebus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Evansville (EVV)plane plane CLT - EVV
    7h 2m
    $143–597

  6. Bus to Charlotte Douglas International Airport, fly to South Bend

    1. Take the bus from Taqueria Guadalajara - Greenville to Charlottebus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to South Bend (SBN)plane plane CLT - SBN
    7h 9m
    $184–832

  7. Bus via Indianapolis Union Station

    1. Take the bus from Taqueria Guadalajara - Greenville to Atlantabus bus Charlotte
    2. Take the bus from Atlanta Bus Station to Indianapolis Union Stationbus bus Greyhound US0100
    17h 5m
    $143–331

Greenville–Spartanburg International Airport (GSP) to Chicago O'Hare International Airport (ORD) flights

Calendar80Weekly Planes
Duration3h 18mAverage Duration
Ticket$67Cheapest Price
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Questions & Answers

Map of how to get from Greenville to Indiana.ExpandLaunch map view
  • Distance: 639.6 mi
  • Duration: 4h 31m

What companies run services between Greenville, SC, USA and Indiana, USA?

You can take a vehicle from Greenville to Indianapolis via Taqueria Guadalajara - Greenville, Atlanta, Doraville Station, Garnett Station, and Atlanta Bus Station in around 16h 55m.

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