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How to get fromGreenville to Iowaby plane, bus (Greyhound, Flixbus), car, bus, or train

Find Transport to Iowa

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There are 6 ways to get from Greenville to Iowa by plane, bus (Greyhound, Flixbus), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Des Moines

    best
    1. Fly from Greenville–Spartanburg International Airport (GSP) to Des Moines (DSM)plane plane GSP - DSM
    4h 53m
    $238–969

  2. Fly to Quad City International Airport

    cheapest
    1. Fly from Greenville–Spartanburg International Airport (GSP) to Quad City International Airport (MLI)plane plane GSP - MLI
    6h 13m
    $133–530

  3. Bus via Kansas City

    1. Take the bus from Taqueria Guadalajara - Greenville to Atlantabus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus
    4. Take the bus from Kansas City to Des Moinesbus bus
    26h 20m
    $233–491

  4. Drive 955.7 mi

    1. Drive from Greenville to Des Moinescar car 955.7 mi
    17h 27m
    $175–252

  5. Bus

    1. Take the bus from Taqueria Guadalajara - Greenville to Atlantabus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Des Moinesbus bus
    26h 30m
    $216–482

  6. Bus, train

    1. Take the bus from Taqueria Guadalajara - Greenville to Atlantabus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the train from St. Louis to Kansas Citytrain train
    4. Take the bus from Kansas City to Des Moinesbus bus
    28h 46m
    $288–606

Greenville–Spartanburg International Airport (GSP) to Des Moines (DSM) flights

Calendar90Weekly Planes
Duration5h 57mAverage Duration
Ticket$179Cheapest Price
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Questions & Answers

Map of how to get from Greenville to Iowa.ExpandLaunch map view
  • Distance: 791 mi
  • Duration: 4h 53m

What companies run services between Greenville, SC, USA and Iowa, USA?

United Airlines, American Airlines, and Delta fly from Greenville–Spartanburg International Airport (GSP) to Des Moines (DSM) hourly. Alternatively, you can take a vehicle from Greenville to Des Moines via Taqueria Guadalajara - Greenville, Atlanta, Doraville Station, Garnett Station, Atlanta Bus Station, St Louis Bus Station, Kansas City Bus Station, and Kansas City in around 26h 20m.

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