Rome2Rio

How to get fromGreenville to Mesaby plane, bus (Greyhound), bus, train, car, or taxi

Find Transport to Mesa

See all options

There are 8 ways to get from Greenville to Mesa by plane, bus (Greyhound), bus, train, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Greenville–Spartanburg International Airport

    best
    1. Fly from Greenville–Spartanburg International Airport (GSP) to Phoenix (PHX)plane plane GSP - PHX
    7h 6m
    $213–750
  2. Bus

    1. Take the bus from Taqueria Guadalajara - Greenville to Atlantabus bus
    2. Take the bus from Atlanta Bus Station to Dallas Bus Stationbus bus
    3. Take the bus from Dallas Bus Station to Phoenix Bus Stationbus bus
    46h 19m
    $345–723
  3. Bus, train via Chicago

    1. Take the bus from Taqueria Guadalajara - Greenville to Atlantabus bus
    2. Take the bus from Atlanta Bus Station to Chicago Train Stationbus bus
    3. Take the train from Chicago Union Station to Flagstafftrain train
    4. Take the bus from Flagstaff Train Station to Tempebus bus
    2d 10h
    $689–1,523
  4. Drive 1,931.3 mi

    1. Drive from Greenville to Mesacar car 1,931.3 mi
    31h
    $353–510
  5. Taxi to Asheville Regional Airport, fly

    1. Take the taxi from Greenville to Asheville-Airport-AVLtaxi taxi
    2. Fly from Asheville Regional Airport (AVL) to Phoenix (PHX)plane plane AVL - PHX
    7h 52m
    $270–766
  6. Drive to Columbia, fly

    1. Drive from Greenville to Columbia-Airport-CAEcar car
    2. Fly from Columbia (CAE) to Phoenix (PHX)plane plane CAE - PHX
    8h 43m
    $341–1,429
  7. Drive to Mcghee Tyson Airport, fly

    1. Drive from Greenville to Mcghee Tyson Airport (TYS)car car
    2. Fly from Mcghee Tyson Airport (TYS) to Phoenix (PHX)plane plane TYS - PHX
    8h 30m
    $213–846
  8. Bus, train

    1. Take the bus from Taqueria Guadalajara - Greenville to Charlottebus bus
    2. Take the train from Charlotte Amtrak Station to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to Tucson Amtrak Stationtrain train
    4. Take the bus from Tucson Downtown to Tempebus bus
    2d 15h
    $787–1,742

Greenville–Spartanburg International Airport (GSP) to Phoenix (PHX) flights

Calendar76Weekly Planes
Duration6h 52mAverage Duration
Ticket$169Cheapest Price
See schedules

Questions & Answers

What companies run services between Greenville, SC, USA and Mesa, AZ, USA?

Southwest Airlines, American Airlines, and two other airlines fly from Greenville–Spartanburg International Airport (GSP) to Phoenix (PHX) every 2 hours. Alternatively, you can take a vehicle from Greenville to Mesa Dr/Main St via Taqueria Guadalajara - Greenville, Atlanta, Doraville Station, Garnett Station, Atlanta Bus Station, Dallas Bus Station, Phoenix, Bus Station (E Buckeye Rd), 24th St Station, Phoenix Sky Harbor Airport/44th Street Sky Train Station, and 44th St/Washington in around 46h 19m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers