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How to get fromGreenville to Middleburgby plane, taxi, bus (Flixbus, Greyhound), car, bus, or bus (Greyhound)

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There are 6 ways to get from Greenville to Middleburg by plane, taxi, bus (Flixbus, Greyhound), car, bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Gainesville Regional Airport, taxi

    best
    1. Fly from Greenville–Spartanburg International Airport (GSP) to Gainesville Regional Airport (GNV)plane plane GSP - GNV
    2. Take the taxi from Gainesville-Airport-GNV to Middleburgtaxi taxi
    4h 39m
    $251–648

  2. Drive 384.1 mi

    cheapest
    1. Drive from Greenville to Middleburgcar car 384.1 mi
    7h 45m
    $71–102

  3. Bus

    1. Take the bus from Taqueria Guadalajara - Greenville to Charlottebus bus Charlotte
    2. Take the bus from Charlotte Bus Station to Jacksonvillebus bus FlixBus 2433
    14h 42m
    $114–280

  4. Fly to Jacksonville, bus, line 900 bus

    1. Fly from Greenville–Spartanburg International Airport (GSP) to Jacksonville (JAX)plane plane GSP - JAX
    2. Take the bus from JRTC Bay P to Blanding Blvd + Orange Park Northwaybus bus
    3. Take the bus from Blanding Blvd + Orange Park Northway to Circle Kbus bus
    7h 49m
    $434–657

  5. Bus via Atlanta

    1. Take the bus from Taqueria Guadalajara - Greenville to Atlantabus bus Charlotte
    2. Take the bus from Atlanta Bus Station to Jacksonvillebus bus FlixBus N2434 / ...
    14h 46m
    $120–287

  6. Bus via LaGrange

    1. Take the bus from Taqueria Guadalajara - Greenville to Atlantabus bus
    2. Take the bus from Atlanta Bus Station to La Grange Bus Stationbus bus
    3. Take the bus from La Grange Bus Station to Jacksonvillebus bus
    18h 16m
    $124–305

Greenville–Spartanburg International Airport (GSP) to Gainesville Regional Airport (GNV) flights

Calendar58Weekly Planes
Duration4h 5mAverage Duration
Ticket$72Cheapest Price
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Questions & Answers

Map of how to get from Greenville to Middleburg.ExpandLaunch map view
  • Distance: 415 mi
  • Duration: 4h 39m

What companies run services between Greenville, SC, USA and Middleburg, FL, USA?

You can take a vehicle from Greenville to Circle K via Taqueria Guadalajara - Greenville, Charlotte, Tryon St & Mellow Dr, Transit Center- Bay A, Transit Center- Bay E, 4th St & Graham St, Charlotte Bus Station, Jacksonville, JRTC Bay P, and Blanding Blvd + Orange Park Northway in around 14h 42m.

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