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How to get fromGreenville to Missouriby plane, bus (Flixbus, Amtrak, Greyhound), car, bus (Greyhound, Flixbus), bus, or train

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There are 6 ways to get from Greenville to Missouri by plane, bus (Flixbus, Amtrak, Greyhound), car, bus (Greyhound, Flixbus), bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Lambert–St. Louis International Airport

    best
    1. Fly from Greenville–Spartanburg International Airport (GSP) to Lambert–St. Louis International Airport (STL)plane plane GSP - STL
    4h 16m
    $154–701

  2. Fly to Springfield-Branson National Airport

    cheapest
    1. Fly from Greenville–Spartanburg International Airport (GSP) to Springfield-Branson National Airport (SGF)plane plane GSP - SGF
    4h 44m
    $147–548

  3. Bus via Carbondale

    1. Take the bus from Taqueria Guadalajara - Greenville to Atlantabus bus
    2. Take the bus from Atlanta Bus Station to Carbondale Intermodal Stationbus bus
    3. Take the bus from Carbondale Intermodal Station to St Louis Bus Stationbus bus
    4. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus
    21h 31m
    $183–406

  4. Drive 894.4 mi

    1. Drive from Greenville to Kansas Citycar car 894.4 mi
    15h 13m
    $164–236

  5. Bus

    1. Take the bus from Taqueria Guadalajara - Greenville to Atlantabus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus
    21h 55m
    $178–401

  6. Bus, train

    1. Take the bus from Taqueria Guadalajara - Greenville to Atlantabus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the train from St. Louis to Kansas Citytrain train
    23h 47m
    $228–521

Greenville–Spartanburg International Airport (GSP) to Lambert–St. Louis International Airport (STL) flights

Calendar122Weekly Planes
Duration5hAverage Duration
Ticket$112Cheapest Price
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Questions & Answers

Map of how to get from Greenville to Missouri.ExpandLaunch map view
  • Distance: 550.7 mi
  • Duration: 4h 16m

What companies run services between Greenville, SC, USA and Missouri, USA?

Southwest Airlines, Delta, and two other airlines fly from Greenville–Spartanburg International Airport (GSP) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, you can take a vehicle from Greenville to Kansas City Bus Station via Taqueria Guadalajara - Greenville, Atlanta, Doraville Station, Garnett Station, Atlanta Bus Station, Carbondale Intermodal Station, and St Louis Bus Station in around 21h 31m.

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