Rome2Rio

How to get fromGreenville to Pittsburghby plane, bus, bus (Greyhound), train, car, or taxi

Find Transport to Pittsburgh

See all options

There are 6 ways to get from Greenville to Pittsburgh by plane, bus, bus (Greyhound), train, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Greenville–Spartanburg International Airport, bus

    best
    1. Fly from Greenville–Spartanburg International Airport (GSP) to Pittsburgh International Airport (PIT)plane plane GSP - PIT
    2. Take the bus from Pittsburgh International Airport to Seventh Ave + William Penn Plbus bus
    3h 15m

  2. Drive 516.4 mi

    cheapest
    1. Drive from Greenville to Pittsburghcar car 516.4 mi
    9h 31m
    $95–137

  3. Bus

    1. Take the bus from Taqueria Guadalajara - Greenville to Charlottebus bus
    2. Take the bus from Charlotte Bus Station to Charleston, WVbus bus
    3. Take the bus from Charleston, WV to Cambridgebus bus
    4. Take the bus from Cambridge, OH to Pittsburgh Intermodal Stationbus bus
    16h 46m
    $126–334

  4. Bus, train

    1. Take the bus from Taqueria Guadalajara - Greenville to Charlottebus bus
    2. Take the train from Charlotte Amtrak Station to Carytrain train
    3. Take the train from Cary to Pittsburgh Amtrak Stationtrain train
    23h 27m
    $298–671

  5. Taxi to Asheville Regional Airport, fly

    1. Take the taxi from Greenville to Asheville-Airport-AVLtaxi taxi
    2. Fly from Asheville Regional Airport (AVL) to Pittsburgh International Airport (PIT)plane plane AVL - PIT
    5h 58m
    $203–554

  6. Bus via Atlanta

    1. Take the bus from Taqueria Guadalajara - Greenville to Atlantabus bus
    2. Take the bus from Atlanta Bus Station to Columbusbus bus
    3. Take the bus from Columbus to Pittsburgh Intermodal Stationbus bus
    25h 40m
    $190–416

Greenville–Spartanburg International Airport (GSP) to Pittsburgh International Airport (PIT) flights

Calendar55Weekly Planes
Duration3h 36mAverage Duration
Ticket$82Cheapest Price
See schedules

Questions & Answers

Map of how to get from Greenville to Pittsburgh.ExpandLaunch map view
  • Distance: 441 mi
  • Duration: 3h 15m

What companies run services between Greenville, SC, USA and Pittsburgh, PA, USA?

You can take a vehicle from Greenville to Pittsburgh Intermodal Station via Taqueria Guadalajara - Greenville, Charlotte, Tryon St & Mellow Dr, Transit Center- Bay A, Transit Center- Bay E, 4th St & Graham St, Charlotte Bus Station, Charleston, WV, Cambridge, and Cambridge, OH in around 16h 46m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers