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How to get fromGreenville to San Diegoby plane, bus (Greyhound, Flixbus), bus, train, car, taxi, or bus (Greyhound, Flixbus, Amtrak)

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There are 6 ways to get from Greenville to San Diego by plane, bus (Greyhound, Flixbus), bus, train, car, taxi, or bus (Greyhound, Flixbus, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Greenville–Spartanburg International Airport

    best
    1. Fly from Greenville–Spartanburg International Airport (GSP) to San Diego International Airport (SAN)plane plane GSP - SAN
    6h 33m
    $251–948

  2. Bus via Irving

    1. Take the bus from Taqueria Guadalajara - Greenville to Atlantabus bus
    2. Take the bus from Atlanta Bus Station to Dallas Bus Stationbus bus
    3. Take the bus from Dallas Bus Station to Los Angeles Union Stationbus bus
    4. Take the bus from Los Angeles Union Station to San Diegobus bus
    2d 10h
    $411–846

  3. Bus, train

    1. Take the bus from Taqueria Guadalajara - Greenville to Charlottebus bus
    2. Take the train from Charlotte Amtrak Station to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to Los Angelestrain train
    4. Take the train from Los Angeles to San Diegotrain train
    3d 3h
    $923–2,046

  4. Drive 2,283.1 mi

    1. Drive from Greenville to San Diegocar car 2,283.1 mi
    35h 45m
    $417–602

  5. Taxi to Asheville Regional Airport, fly

    1. Take the taxi from Greenville to Asheville-Airport-AVLtaxi taxi
    2. Fly from Asheville Regional Airport (AVL) to San Diego International Airport (SAN)plane plane AVL - SAN
    7h 15m
    $298–864

  6. Bus

    1. Take the bus from Taqueria Guadalajara - Greenville to Atlantabus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Los Angeles Union Stationbus bus
    4. Take the bus from Los Angeles to San Diegobus bus
    2d 14h
    $463–941

Greenville–Spartanburg International Airport (GSP) to San Diego International Airport (SAN) flights

Calendar73Weekly Planes
Duration7h 6mAverage Duration
Ticket$213Cheapest Price
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Questions & Answers

Map of how to get from Greenville to San Diego.ExpandLaunch map view
  • Distance: 2,017.3 mi
  • Duration: 6h 33m

What companies run services between Greenville, SC, USA and San Diego, CA, USA?

Southwest Airlines, American Airlines, and two other airlines fly from Greenville–Spartanburg International Airport (GSP) to San Diego International Airport (SAN) every 3 hours. Alternatively, you can take a vehicle from Greenville to San Diego via Taqueria Guadalajara - Greenville, Atlanta, Doraville Station, Garnett Station, Atlanta Bus Station, Dallas Bus Station, and Los Angeles Union Station in around 2d 10h.

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