There are 4 ways to get from Greenville to Tupelo by plane, car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Golden Triangle Regional Airport, drive
best- Fly from Greenville–Spartanburg International Airport (GSP) to Golden Triangle Regional Airport (GTR)plane GSP - GTR
- Drive from Golden Triangle Regional Airport (GTR) to Tupelocar
4h 44m$117–465Drive 419 mi
cheapest- Drive from Greenville to Tupelocar 419 mi
7h 7m$77–111Bus
- Take the bus from Taqueria Guadalajara - Greenville to Atlantabus Charlotte
- Take the bus from Atlanta Bus Station to Tupelobus Greyhound US0610
11h 14m$114–265Fly to Tupelo Regional Airport
- Fly from Greenville–Spartanburg International Airport (GSP) to Tupelo Regional Airport (TUP)plane GSP - TUP
5h 58m$120–466
Greenville–Spartanburg International Airport (GSP) to Golden Triangle Regional Airport (GTR) flights
Questions & Answers
The cheapest way to get from Greenville to Tupelo is to drive which costs $75 - $110 and takes 7h 7m.
The fastest way to get from Greenville to Tupelo is to fly and drive which takes 4h 44m and costs $110 - $470.
No, there is no direct bus from Greenville to Tupelo. However, there are services departing from Taqueria Guadalajara - Greenville and arriving at Tupelo via Atlanta Bus Station. The journey, including transfers, takes approximately 11h 14m.
The distance between Greenville and Tupelo is 456 miles. The road distance is 421.5 miles.
The best way to get from Greenville to Tupelo without a car is to bus which takes 11h 14m and costs $110 - $270.
It takes approximately 4h 44m to get from Greenville to Tupelo, including transfers.
Greenville to Tupelo bus services, operated by Tornado Bus Company, depart from Taqueria Guadalajara - Greenville station.
The best way to get from Greenville to Tupelo is to bus which takes 11h 14m and costs $110 - $270. Alternatively, you can fly, which costs $120 - $470 and takes 5h 58m.
Greenville to Tupelo bus services, operated by Tornado Bus Company, arrive at Atlanta station.
Tupelo is 1h behind Greenville. It is currently 4:46 PM in Greenville and 3:46 PM in Tupelo.
What companies run services between Greenville, SC, USA and Tupelo, MS, USA?
You can take a vehicle from Greenville to Tupelo via Taqueria Guadalajara - Greenville, Atlanta, Doraville Station, Garnett Station, Atlanta Bus Station, and Tupelo in around 11h 14m. Alternatively, American Airlines, Corporate Flight Management Inc, and two other airlines fly from Greenville–Spartanburg International Airport (GSP) to Tupelo Regional Airport (TUP) 3 times a day.
- Website
- contouraviation.com
Flights from Greenville–Spartanburg International Airport to Tupelo Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 58m
- When
- Every day
- Estimated price
- $140–650
Flights from Greenville–Spartanburg International Airport to Tupelo Regional Airport via Nashville
- Ave. Duration
- 6h 30m
- When
- Every day
- Estimated price
- $65–400
Flights from Greenville–Spartanburg International Airport to Tupelo Regional Airport via Atlanta, Nashville
- Ave. Duration
- 6h 21m
- When
- Every day
- Estimated price
- $75–420
Flights from Greenville–Spartanburg International Airport to Tupelo Regional Airport via Charlotte, Nashville
- Ave. Duration
- 7h 13m
- When
- Sunday and Thursday
- Estimated price
- $80–430
- Website
- delta.com
Flights from Greenville–Spartanburg International Airport to Golden Triangle Regional Airport via Atlanta
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- $65–400
- Phone
- +1 888 358 6762
- [email protected]
- Website
- tornadobus.com
Bus from Taqueria Guadalajara - Greenville to Atlanta
- Ave. Duration
- 3h 23m
- Frequency
- Once daily
- Estimated price
- $45–150
- Schedules at
- tornadobus.com
- Adults 11-59
- $45–150
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Atlanta Bus Station to Tupelo
- Ave. Duration
- 5h 55m
- Frequency
- Twice daily
- Estimated price
- $40–80
- Website
- https://www.greyhound.com/
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More Questions & Answers
Yes, the driving distance between Greenville to Tupelo is 421 miles. It takes approximately 7h 7m to drive from Greenville to Tupelo.
Book your Greenville to Tupelo bus tickets online with Omio.
There are 33+ hotels available in Tupelo.




