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How to get fromGreenville to Winston-Salemby bus (Greyhound), car, plane, bus, or train

Find Transport to Winston-Salem

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There are 5 ways to get from Greenville to Winston-Salem by bus (Greyhound), car, plane, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Taqueria Guadalajara - Greenville to Charlottebus bus Charlotte
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus Greyhound US0670
    5h 46m
    $64–204

  2. Drive 165.5 mi

    cheapest
    1. Drive from Greenville to Winston-Salemcar car 165.5 mi
    3h 17m
    $31–44

  3. Fly to Piedmont Triad International Airport

    1. Fly from Greenville–Spartanburg International Airport (GSP) to Piedmont Triad International Airport (GSO)plane plane GSP - GSO
    4h 22m
    $135–621

  4. Bus, train

    1. Take the bus from Taqueria Guadalajara - Greenville to Charlottebus bus
    2. Take the train from Charlotte Amtrak Station to Greensborotrain train
    3. Take the bus from Greensboro Bus Stop to Winston Salem(Trans Center)bus bus
    7h 21m
    $91–234

  5. Fly to Charlotte Douglas International Airport, bus

    1. Fly from Greenville–Spartanburg International Airport (GSP) to Charlotte Douglas International Airport (CLT)plane plane GSP - CLT
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    4h 34m
    $112–574

Greenville–Spartanburg International Airport (GSP) to Piedmont Triad International Airport (GSO) flights

Calendar110Weekly Planes
Duration4h 14mAverage Duration
Ticket$77Cheapest Price
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Questions & Answers

Map of how to get from Greenville to Winston-Salem.ExpandLaunch map view
  • Distance: 196.7 mi
  • Duration: 5h 46m

What companies run services between Greenville, SC, USA and Winston-Salem, NC, USA?

You can take a vehicle from Greenville to Winston Salem(Trans Center) via Taqueria Guadalajara - Greenville, Charlotte, Tryon St & Mellow Dr, Transit Center- Bay A, Transit Center- Bay E, 4th St & Graham St, and Charlotte Bus Station in around 5h 46m. Alternatively, American Airlines, Delta, and United Airlines fly from Greenville–Spartanburg International Airport (GSP) to Piedmont Triad International Airport (GSO) hourly.

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