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How to get fromGreenville to Ypsilantiby plane, bus (Greyhound, Amtrak), bus, train, car, taxi, or bus (Greyhound)

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There are 6 ways to get from Greenville to Ypsilanti by plane, bus (Greyhound, Amtrak), bus, train, car, taxi, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Greenville–Spartanburg International Airport

    best
    1. Fly from Greenville–Spartanburg International Airport (GSP) to Detroit (DTW)plane plane GSP - DTW
    2h 22m
    $196–718

  2. Drive 637 mi

    cheapest
    1. Drive from Greenville to Ypsilanticar car 637 mi
    11h 54m
    $117–168

  3. Bus

    1. Take the bus from Taqueria Guadalajara - Greenville to Atlantabus bus
    2. Take the bus from Atlanta Bus Station to Toledo Bus Stopbus bus
    3. Take the bus from Toledo to Ann Arbor Amtrak Stationbus bus
    22h 50m
    $182–388

  4. Bus, train

    1. Take the bus from Taqueria Guadalajara - Greenville to Charlottebus bus
    2. Take the train from Charlotte Amtrak Station to Raleigh Union Stationtrain train
    3. Take the train from Raleigh Union Station to Toledotrain train
    4. Take the bus from Toledo to Ann Arbor Amtrak Stationbus bus
    30h 35m
    $415–896

  5. Taxi to Asheville Regional Airport, fly

    1. Take the taxi from Greenville to Asheville-Airport-AVLtaxi taxi
    2. Fly from Asheville Regional Airport (AVL) to Detroit (DTW)plane plane AVL - DTW
    5h 1m
    $278–724

  6. Bus via Columbus

    1. Take the bus from Taqueria Guadalajara - Greenville to Atlantabus bus
    2. Take the bus from Atlanta Bus Station to Columbusbus bus
    3. Take the bus from Columbus - Mound St to Ann Arbor Amtrak Stationbus bus
    26h 45m
    $178–423

Greenville–Spartanburg International Airport (GSP) to Detroit (DTW) flights

Calendar71Weekly Planes
Duration3h 32mAverage Duration
Ticket$103Cheapest Price
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Questions & Answers

Map of how to get from Greenville to Ypsilanti.ExpandLaunch map view
  • Distance: 539.8 mi
  • Duration: 2h 22m

What companies run services between Greenville, SC, USA and Ypsilanti, MI, USA?

Delta, Southwest Airlines, and American Airlines fly from Greenville–Spartanburg International Airport (GSP) to Detroit (DTW) every 3 hours. Alternatively, you can take a vehicle from Greenville to YTC - EndPt via Taqueria Guadalajara - Greenville, Atlanta, Doraville Station, Garnett Station, Atlanta Bus Station, Toledo, Ann Arbor Amtrak Station, Beakes + Summit, and BTC - Fourth Ave Stop 1 in around 22h 50m.

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