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How to get fromGreenville Station to Chicagoby plane, bus (Greyhound, Flixbus), car, taxi, or bus (Greyhound)

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There are 7 ways to get from Greenville Station to Chicago by plane, bus (Greyhound, Flixbus), car, taxi, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Greenville–Spartanburg International Airport to Chicago O'Hare International Airport

    best
    1. Fly from Greenville–Spartanburg International Airport (GSP) to Chicago O'Hare International Airport (ORD)plane plane GSP - ORD
    3h 13m
    $108–423

  2. Bus

    1. Take the bus from Taqueria Guadalajara - Greenville to Atlantabus bus Charlotte
    2. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus FlixBus 2512 / ...
    19h 37m
    $174–392

  3. Drive 669 mi

    1. Drive from Greenville Station to Chicagocar car 669 mi
    12h 43m
    $123–177

  4. Taxi to Asheville Regional Airport, fly to Chicago O'Hare International Airport

    1. Take the taxi from Greenville Station to Asheville-Airport-AVLtaxi taxi
    2. Fly from Asheville Regional Airport (AVL) to Chicago O'Hare International Airport (ORD)plane plane AVL - ORD
    3h 50m
    $191–459

  5. Fly Greenville–Spartanburg International Airport to Chicago Midway International Airport

    1. Fly from Greenville–Spartanburg International Airport (GSP) to Chicago Midway International Airport (MDW)plane plane GSP - MDW
    4h 40m
    $128–503

  6. Taxi to Asheville Regional Airport, fly to Chicago Midway International Airport

    1. Take the taxi from Greenville Station to Asheville-Airport-AVLtaxi taxi
    2. Fly from Asheville Regional Airport (AVL) to Chicago Midway International Airport (MDW)plane plane AVL - MDW
    6h 6m
    $211–529

  7. Bus via Chicago Train Station

    1. Take the bus from Taqueria Guadalajara - Greenville to Atlantabus bus Charlotte
    2. Take the bus from Atlanta Bus Station to Chicago Train Stationbus bus Greyhound US0100
    21h 11m
    $174–392

Greenville–Spartanburg International Airport (GSP) to Chicago O'Hare International Airport (ORD) flights

Calendar80Weekly Planes
Duration3h 18mAverage Duration
Ticket$69Cheapest Price
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Questions & Answers

Map of how to get from Greenville Station to Chicago.ExpandLaunch map view
  • Distance: 609.5 mi
  • Duration: 3h 13m

What companies run services between Greenville Station, SC, USA and Chicago, IL, USA?

American Airlines, United Airlines, and Delta fly from Greenville–Spartanburg International Airport (GSP) to Chicago O'Hare International Airport (ORD) every 2 hours. Alternatively, you can take a vehicle from Greenville Station to Chicago Bus Station via Taqueria Guadalajara - Greenville, Atlanta, Doraville Station, Garnett Station, and Atlanta Bus Station in around 19h 37m.

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