Rome2Rio

How to get fromGreenville Station to St. Louisby plane, bus (Flixbus, Amtrak), car, taxi, or bus (Greyhound, Flixbus)

Find Transport to St. Louis

See all options

There are 6 ways to get from Greenville Station to St. Louis by plane, bus (Flixbus, Amtrak), car, taxi, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Greenville–Spartanburg International Airport

    best
    1. Fly from Greenville–Spartanburg International Airport (GSP) to Lambert–St. Louis International Airport (STL)plane plane GSP - STL
    4h 16m
    $154–701

  2. Drive 648.1 mi

    cheapest
    1. Drive from Greenville Station to St. Louiscar car 648.1 mi
    11h 4m
    $119–171

  3. Bus via Carbondale

    1. Take the bus from Taqueria Guadalajara - Greenville to Atlantabus bus
    2. Take the bus from Atlanta Bus Station to Carbondale Intermodal Stationbus bus
    3. Take the bus from Carbondale to St. Louisbus bus
    16h 37m
    $149–352

  4. Taxi to Asheville Regional Airport, fly

    1. Take the taxi from Greenville Station to Asheville-Airport-AVLtaxi taxi
    2. Fly from Asheville Regional Airport (AVL) to Lambert–St. Louis International Airport (STL)plane plane AVL - STL
    5h 21m
    $242–717

  5. Drive to Columbia, fly

    1. Drive from Greenville Station to Columbia-Airport-CAEcar car
    2. Fly from Columbia (CAE) to Lambert–St. Louis International Airport (STL)plane plane CAE - STL
    6h 12m
    $262–1,330

  6. Bus

    1. Take the bus from Taqueria Guadalajara - Greenville to Atlantabus bus Charlotte
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus Greyhound US0186
    16h 56m
    $149–342

Greenville–Spartanburg International Airport (GSP) to Lambert–St. Louis International Airport (STL) flights

Calendar122Weekly Planes
Duration5hAverage Duration
Ticket$112Cheapest Price
See schedules

Questions & Answers

Map of how to get from Greenville Station to St. Louis.ExpandLaunch map view
  • Distance: 550.7 mi
  • Duration: 4h 16m

What companies run services between Greenville Station, SC, USA and St. Louis, MO, USA?

Southwest Airlines, Delta, and two other airlines fly from Greenville–Spartanburg International Airport (GSP) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, you can take a vehicle from Greenville Station to St. Louis via Taqueria Guadalajara - Greenville, Atlanta, Doraville Station, Garnett Station, Atlanta Bus Station, and Carbondale in around 16h 37m.

Airlines
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers