There are 9 ways to get from Grenoble to Karlsruhe by train (TGV), bus, car, train, plane, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Grenoble to Lyon Part Dieutrain Ter
- Take the train from Lyon Part Dieu to Karlsruhe Hbftrain Tgv
7h 7m€133–219Bus
cheapest- Take the bus from Grenoble to Lyonbus S1777 / ...
- Take the bus from Lyon to Karlsruhe central train stationbus FlixBus N1135 / ...
10h 15m€48–89Drive 583.5 km
- Drive from Grenoble to Karlsruhecar 583.5 km
5h 32m€94–136Train to Lyon–Saint Exupéry Airport, fly to Strasbourg International Airport, train
- Take the train from Grenoble to Lyon-Saint Exupery Tgvtrain
- Fly from Lyon–Saint Exupéry Airport (LYS) to Strasbourg International Airport (SXB)plane LYS - SXB
- Take the train from Strasbourg to Karlsruhe Hbftrain
5h 7m€134–387Train via Basel
- Take the train from Grenoble to Genevetrain Ter
- Take the train from Genève to Renens VDtrain Ic1 / ...
- Take the train from Renens VD to Basel SBBtrain
- Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain 12 / ...
8h 8m€140–334Bus via Freiburg im Breisgau
- Take the bus from Grenoble to Freiburgbus FlixBus N872
- Take the bus from Freiburg to Karlsruhe central train stationbus FlixBus N1135 / ...
12h 36m€56–83Train to Lyon–Saint Exupéry Airport, fly to Frankfurt, train
- Take the train from Grenoble to Lyon-Saint Exupery Tgvtrain
- Fly from Lyon–Saint Exupéry Airport (LYS) to Frankfurt (FRA)plane LYS - FRA
- Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain
6h 36m€144–394Train to Geneva International Airport, fly to Zurich Airport, train
- Take the train from Grenoble to Genevetrain
- Fly from Geneva International Airport (GVA) to Zurich Airport (ZRH)plane GVA - ZRH
- Take the train from Zürich HB to Basel SBBtrain
- Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain
8h 7m€205–607Train to Geneva International Airport, fly to Frankfurt, train
- Take the train from Grenoble to Genevetrain
- Fly from Geneva International Airport (GVA) to Frankfurt (FRA)plane GVA - FRA
- Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain
8h 3m€156–363
Grenoble to Karlsruhe by train
Comparing Your Travel Options
The cheapest way to get from Grenoble to Karlsruhe is to bus via Freiburg im Breisgau which costs €55 - €85 and takes 12h 36m.
The fastest way to get from Grenoble to Karlsruhe is to train and fly which takes 5h 7m and costs €130 - €390.
No, there is no direct bus from Grenoble to Karlsruhe station. However, there are services departing from Grenoble and arriving at Karlsruhe central train station via Lyon. The journey, including transfers, takes approximately 10h 15m.
No, there is no direct train from Grenoble to Karlsruhe. However, there are services departing from Grenoble and arriving at Karlsruhe Hbf via Lyon Part Dieu. The journey, including transfers, takes approximately 7h 7m.
The distance between Grenoble and Karlsruhe is 712 km. The road distance is 583.5 km.
The best way to get from Grenoble to Karlsruhe without a car is to train which takes 7h 7m and costs €130 - €220.
It takes approximately 7h 7m to get from Grenoble to Karlsruhe, including transfers.
Grenoble to Karlsruhe bus services, operated by FlixBus, depart from Grenoble station.
Grenoble to Karlsruhe train services, operated by Société Nationale des Chemins de fer Français (SNCF), depart from Grenoble station.
The best way to get from Grenoble to Karlsruhe is to train which takes 7h 7m and costs €130 - €220. Alternatively, you can bus, which costs €45 - €90 and takes 10h 15m.
What companies run services between Grenoble, France and Karlsruhe, Germany?
You can take a train from Grenoble to Karlsruhe Hbf via Lyon Part Dieu in around 7h 7m. Alternatively, you can take a bus from Grenoble to Karlsruhe central train station via Lyon in around 10h 15m.
- Website
- swiss.com
Flights from Geneva International Airport to Zurich Airport
- Ave. Duration
- 53 min
- When
- Every day
- Estimated price
- €130–380
Flights from Geneva International Airport to Frankfurt
- Ave. Duration
- 1h 17m
- When
- Every day
- Estimated price
- €100–410
Flights from Geneva International Airport to Frankfurt via Zurich Airport
- Ave. Duration
- 3h 17m
- When
- Every day
- Estimated price
- €100–230
- Website
- lufthansa.com
Flights from Lyon–Saint Exupéry Airport to Frankfurt
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €65–430
Flights from Lyon–Saint Exupéry Airport to Frankfurt via Munich
- Ave. Duration
- 3h 33m
- When
- Every day
- Estimated price
- €70–360
Flights from Geneva International Airport to Frankfurt
- Ave. Duration
- 1h 17m
- When
- Every day
- Estimated price
- €100–410
Flights from Geneva International Airport to Frankfurt via Munich
- Ave. Duration
- 3h 5m
- When
- Thursday, Saturday, and Sunday
- Estimated price
- €100–230
- Website
- airbus.com
Flights from Lyon–Saint Exupéry Airport to Frankfurt
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €65–210
- Website
- twinjet.fr
Flights from Lyon–Saint Exupéry Airport to Strasbourg International Airport
- Ave. Duration
- 1h 10m
- When
- Monday to Friday
- Estimated price
- €650–1,500
- Website
- airdolomiti.it
Flights from Lyon–Saint Exupéry Airport to Frankfurt
- Ave. Duration
- 1h 25m
- When
- Saturday and Sunday
- Estimated price
- €140–430
Flights from Geneva International Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €130–410
- Website
- brusselsairlines.com
Flights from Geneva International Airport to Frankfurt via Brussels
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- €220–280
- Website
- airfrance.com
Flights from Lyon–Saint Exupéry Airport to Frankfurt via Paris Charles de Gaulle
- Ave. Duration
- 3h 30m
- When
- Every day
- Estimated price
- €45–290
Rome2Rio's guide to Société Nationale des Chemins de fer Français (SNCF)
Contact DetailsContact Details
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Grenoble to Lyon Part Dieu
- Ave. Duration
- 1h 23m
- Frequency
- Hourly
- Estimated price
- €23–40
- Website
- Oui.SNCF
Train from Grenoble to Lyon-Saint Exupery Tgv
- Ave. Duration
- 59 min
- Frequency
- Once daily
- Estimated price
- €20–35
- Website
- Oui.SNCF
Train from Strasbourg to Karlsruhe Hbf
- Ave. Duration
- 49 min
- Frequency
- Twice a week
- Estimated price
- €14–24
- Website
- Oui.SNCF
Train from Grenoble to Geneve
- Ave. Duration
- 2h 12m
- Frequency
- Every 4 hours
- Estimated price
- €30–50
- Website
- Oui.SNCF
Train from Grenoble to Lyon-Saint Exupery Tgv
- Ave. Duration
- 59 min
- Frequency
- Once daily
- Estimated price
- €20–35
- Website
- Oui.SNCF
Train from Grenoble to Geneve
- Ave. Duration
- 2h 12m
- Frequency
- Every 4 hours
- Estimated price
- €30–50
- Website
- Oui.SNCF
Train from Grenoble to Geneve
- Ave. Duration
- 2h 12m
- Frequency
- Every 4 hours
- Estimated price
- €30–50
- Website
- Oui.SNCF
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Grenoble to Lyon Part Dieu
- Ave. Duration
- 1h 23m
- Frequency
- Twice a week
- Estimated price
- €26–40
- Website
- TGV inOui
Train from Lyon Part Dieu to Karlsruhe Hbf
- Ave. Duration
- 4h 44m
- Frequency
- Once daily
- Estimated price
- €110–180
- Website
- TGV inOui
Train from Grenoble to Lyon-Saint Exupery Tgv
- Ave. Duration
- 1h 3m
- Frequency
- Every 4 hours
- Estimated price
- €23–35
- Website
- TGV inOui
Train from Strasbourg to Karlsruhe Hbf
- Ave. Duration
- 44 min
- Frequency
- 5 times a day
- Estimated price
- €15–24
- Website
- TGV inOui
Train from Grenoble to Lyon-Saint Exupery Tgv
- Ave. Duration
- 1h 3m
- Frequency
- Every 4 hours
- Estimated price
- €23–35
- Website
- TGV inOui
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Strasbourg to Karlsruhe Hbf
- Ave. Duration
- 39 min
- Frequency
- Every 4 hours
- Estimated price
- €13–30
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 41m
- Frequency
- Hourly
- Estimated price
- €30–75
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 8m
- Frequency
- Every 3 hours
- Estimated price
- €22–50
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 41m
- Frequency
- Hourly
- Estimated price
- €30–75
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 8m
- Frequency
- Every 3 hours
- Estimated price
- €22–50
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Genève to Renens VD
- Ave. Duration
- 45 min
- Frequency
- Every 15 minutes
- Estimated price
- €20–35
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Renens VD to Basel SBB
- Ave. Duration
- 2h 15m
- Frequency
- Hourly
- Estimated price
- €60–100
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Zürich HB to Basel SBB
- Ave. Duration
- 1h 13m
- Frequency
- Every 20 minutes
- Estimated price
- €30–55
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +43 5 1717
- Website
- Österreichische Bundesbahnen
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 58m
- Frequency
- 3 times a day
- Estimated price
- €40–65
- Website
- Österreichische Bundesbahnen
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 58m
- Frequency
- 3 times a day
- Estimated price
- €40–65
- Website
- Österreichische Bundesbahnen
- Phone
- +39 06 68475475
- [email protected]
- Website
- Trenitalia Eurocity
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- €45–95
- Website
- Trenitalia Eurocity
- 1st Class
- €65–95
- 2nd Class
- €45–65
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- €45–95
- Website
- Trenitalia Eurocity
- 1st Class
- €65–95
- 2nd Class
- €45–65
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 2h 54m
- Frequency
- Once daily
- Estimated price
- €35–150
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 2h 54m
- Frequency
- Once daily
- Estimated price
- €35–150
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 53m
- Frequency
- Once daily
- Estimated price
- €14–28
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 53m
- Frequency
- Once daily
- Estimated price
- €14–28
- Website
- Nederlandse Spoorwegen (NS)
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Grenoble to Lyon
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- €9–14
- Website
- Flixbus
Bus from Lyon to Karlsruhe central train station
- Ave. Duration
- 7h 55m
- Frequency
- 4 times a day
- Estimated price
- €50–75
- Website
- Flixbus
Bus from Grenoble to Freiburg
- Ave. Duration
- 7h 50m
- Frequency
- Twice daily
- Estimated price
- €40–60
- Website
- Flixbus
Bus from Freiburg to Karlsruhe central train station
- Ave. Duration
- 2h 25m
- Frequency
- Every 4 hours
- Estimated price
- €14–21
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Grenoble to Lyon
- Ave. Duration
- 1h 45m
- Frequency
- Hourly
- Estimated price
- €7–13
- Website
- BlaBlaCar Bus
Bus from Lyon to Karlsruhe central train station
- Ave. Duration
- 8h 45m
- Frequency
- Every 4 hours
- Estimated price
- €40–70
- Website
- BlaBlaCar Bus
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Booking & Getting There
Grenoble to Karlsruhe bus services, operated by FlixBus, arrive at Lyon station.
Grenoble to Karlsruhe train services, operated by Société Nationale des Chemins de fer Français (SNCF), arrive at Lyon Part Dieu station.
Yes, the driving distance between Grenoble to Karlsruhe is 584 km. It takes approximately 5h 32m to drive from Grenoble to Karlsruhe.
Book your Grenoble to Karlsruhe train tickets online with Omio.
Book your Grenoble to Karlsruhe bus tickets online with Omio and FlixBus.
There are 894+ hotels available in Karlsruhe.













































