There are 7 ways to get from Grenoble to Madrid by train, plane, train (TGV, Renfe, Ouigo), bus, car, or train (TGV, Renfe)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Lyon–Saint Exupéry Airport, fly
best- Take the train from Grenoble to Lyon-Saint Exupery Tgvtrain
- Fly from Lyon–Saint Exupéry Airport (LYS) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane LYS - MAD
5h 29m€79–250Train via Barcelona
- Take the train from Grenoble to Valence Tgv Rhone-Alpes Sudtrain Ter
- Take the train from Valence Tgv Rhone-Alpes Sud to Barcelona-Santstrain Tgv
- Take the train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandestrain Ave
9h 47m€140–393Bus
- Take the bus from Grenoble - Bus Station to Lyon - Gerland Bus Stationbus BlaBlaCar Bus
- Take the bus from Lyon - Gerland Bus Station to Estación Sur de Autobusesbus BlaBlaCar Bus
19h 50m€118–216Drive 1,188 km
- Drive from Grenoble to Madridcar 1,188 km
11h 33m€187–269Train to Geneva International Airport, fly
- Take the train from Grenoble to Genevetrain
- Fly from Geneva International Airport (GVA) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane GVA - MAD
7h 1m€91–296Train
- Take the train from Grenoble to Valence Tgv Rhone-Alpes Sudtrain Ter
- Take the train from Valence Tgv Rhone-Alpes Sud to Nimestrain Tgv
- Take the train from Nimes to Madrid-Puerta de Atocha-Almudena Grandestrain
10h 2m€165–303Bus via Madrid
- Take the bus from Grenoble - Bus Station to Lyon - Gerland Bus Stationbus BlaBlaCar Bus
- Take the bus from Lyon to Madridbus FlixBus N1149
20h 10m€108–186
Grenoble to Madrid by train
Questions & Answers
The cheapest way to get from Grenoble to Madrid is to bus via Madrid which costs €100 - €190 and takes 20h 10m.
The fastest way to get from Grenoble to Madrid is to train and fly which takes 5h 29m and costs €75 - €250.
No, there is no direct bus from Grenoble station to Madrid. However, there are services departing from Grenoble - Bus Station and arriving at Estación Sur de Autobuses via Lyon - Gerland Bus Station. The journey, including transfers, takes approximately 19h 50m.
No, there is no direct train from Grenoble to Madrid. However, there are services departing from Grenoble and arriving at Madrid-Puerta de Atocha-Almudena Grandes via Valence Tgv Rhone-Alpes Sud and Barcelona-Sants. The journey, including transfers, takes approximately 9h 47m.
The distance between Grenoble and Madrid is 1037 km. The road distance is 1188 km.
The best way to get from Grenoble to Madrid without a car is to train via Barcelona which takes 9h 47m and costs €140 - €400.
It takes approximately 5h 29m to get from Grenoble to Madrid, including transfers.
Grenoble to Madrid bus services, operated by BlaBlaCar Bus, depart from Grenoble - Bus Station.
Grenoble to Madrid train services, operated by Société Nationale des Chemins de fer Français (SNCF), depart from Grenoble station.
The best way to get from Grenoble to Madrid is to train via Barcelona which takes 9h 47m and costs €140 - €400. Alternatively, you can bus, which costs €110 - €220 and takes 19h 50m.
What companies run services between Grenoble, France and Madrid, Spain?
You can take a train from Grenoble to Madrid-Puerta de Atocha-Almudena Grandes via Valence Tgv Rhone-Alpes Sud and Barcelona-Sants in around 9h 47m. Alternatively, you can take a bus from Grenoble - Bus Station to Estación Sur de Autobuses via Lyon - Gerland Bus Station in around 19h 50m.
- Website
- iberia.com
Flights from Lyon–Saint Exupéry Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- €45–170
Flights from Lyon–Saint Exupéry Airport to Adolfo Suárez Madrid–Barajas Airport via Barcelona
- Ave. Duration
- 4h 15m
- When
- Monday, Friday, and Wednesday
- Estimated price
- €90–200
Flights from Geneva International Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 5m
- When
- Every day
- Estimated price
- €60–160
- Website
- vueling.com
Flights from Lyon–Saint Exupéry Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- €45–170
Flights from Lyon–Saint Exupéry Airport to Adolfo Suárez Madrid–Barajas Airport via Barcelona
- Ave. Duration
- 4h 15m
- When
- Monday, Friday, and Wednesday
- Estimated price
- €90–200
Flights from Geneva International Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 5m
- When
- Every day
- Estimated price
- €60–160
- Website
- easyjet.com
Flights from Lyon–Saint Exupéry Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 5m
- When
- Sunday
- Estimated price
- €60–190
Flights from Geneva International Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 15m
- When
- Monday and Wednesday
- Estimated price
- €40–270
- Website
- aireuropa.com
Flights from Geneva International Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 1h 55m
- When
- Every day
- Estimated price
- €55–190
- Website
- volotea.com
Flights from Lyon–Saint Exupéry Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h
- When
- Wednesday
- Estimated price
- €35–170
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Grenoble to Lyon-Saint Exupery Tgv
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- €23–40
- Website
- TGV inOui
Train from Valence Tgv Rhone-Alpes Sud to Barcelona-Sants
- Ave. Duration
- 4h 35m
- Frequency
- 5 times a day
- Estimated price
- €110–180
- Website
- TGV inOui
Train from Valence Tgv Rhone-Alpes Sud to Nimes
- Ave. Duration
- 46 min
- Frequency
- Hourly
- Estimated price
- €30–55
- Website
- TGV inOui
Rome2Rio's guide to Société Nationale des Chemins de fer Français (SNCF)
Contact DetailsContact Details
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Grenoble to Valence Tgv Rhone-Alpes Sud
- Ave. Duration
- 1h 3m
- Frequency
- Hourly
- Estimated price
- €14–29
- Website
- Oui.SNCF
Train from Grenoble to Geneve
- Ave. Duration
- 2h 13m
- Frequency
- Every 2 hours
- Estimated price
- €28–60
- Website
- Oui.SNCF
Train from Grenoble to Valence Tgv Rhone-Alpes Sud
- Ave. Duration
- 1h 3m
- Frequency
- Hourly
- Estimated price
- €14–29
- Website
- Oui.SNCF
Train from Valence Tgv Rhone-Alpes Sud to Nimes
- Ave. Duration
- 46 min
- Frequency
- Once a week
- Estimated price
- €27–55
- Website
- Oui.SNCF
- Phone
- +33 4 13 94 30 50
- Website
- Zou! Lignes Express Régionales
Train from Grenoble to Valence Tgv Rhone-Alpes Sud
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- €22–45
- Website
- Zou! Lignes Express Régionales
Train from Grenoble to Valence Tgv Rhone-Alpes Sud
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- €22–45
- Website
- Zou! Lignes Express Régionales
Rome2Rio's guide to Renfe Viajeros
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- Renfe Viajeros
Train from Valence Tgv Rhone-Alpes Sud to Barcelona-Sants
- Ave. Duration
- 4h 12m
- Frequency
- Twice daily
- Estimated price
- €70–110
- Website
- Renfe Viajeros
Train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 3h 2m
- Frequency
- 4 times a day
- Estimated price
- €75–120
- Website
- Renfe Viajeros
Train from Valence Tgv Rhone-Alpes Sud to Nimes
- Ave. Duration
- 44 min
- Frequency
- 4 times a day
- Estimated price
- €20–35
- Website
- Renfe Viajeros
Train from Nimes to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 6h 51m
- Frequency
- Twice daily
- Estimated price
- €130–200
- Website
- Renfe Viajeros
Rome2Rio's guide to Renfe AVE
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- Renfe AVE
Train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 3h 2m
- Frequency
- Every 30 minutes
- Estimated price
- €90–170
- Website
- Renfe AVE
- Phone
- +34 900 926 851
- [email protected]
- Website
- Iryo
Train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 3h 19m
- Frequency
- Hourly
- Estimated price
- €60–120
- Website
- Iryo
- Phone
- +34 900 759 781
- Website
- Ouigo
Train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 3h 17m
- Frequency
- Every 2 hours
- Estimated price
- €55–100
- Website
- Ouigo
- Phone
- +32 70 79 79 79
- Website
- Belgian Railways
Train from Valence Tgv Rhone-Alpes Sud to Nimes
- Ave. Duration
- 44 min
- Frequency
- 6 times a week
- Estimated price
- €27–60
- Website
- Belgian Railways
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Grenoble - Bus Station to Lyon - Gerland Bus Station
- Ave. Duration
- 1h 25m
- Frequency
- Hourly
- Estimated price
- €9–17
- Website
- BlaBlaCar Bus
Bus from Lyon - Gerland Bus Station to Estación Sur de Autobuses
- Ave. Duration
- 17h 25m
- Frequency
- 5 times a day
- Estimated price
- €110–200
- Website
- BlaBlaCar Bus
Bus from Grenoble - Bus Station to Lyon - Gerland Bus Station
- Ave. Duration
- 1h 25m
- Frequency
- Hourly
- Estimated price
- €9–17
- Website
- BlaBlaCar Bus
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Grenoble - Bus Station to Lyon - Gerland Bus Station
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- €8–14
- Website
- Flixbus
Bus from Grenoble - Bus Station to Lyon - Gerland Bus Station
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- €8–14
- Website
- Flixbus
Bus from Lyon to Madrid
- Ave. Duration
- 17h 45m
- Frequency
- Once daily
- Estimated price
- €100–170
- Website
- Flixbus
Want to know more about travelling around Spain
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
5 delightfully under-the-radar French towns you need to visit
Read the travel guide
Train travel in France: A guide to SNCF
Read the travel guide
Train travel in Spain: A guide to Renfe
Read the travel guide
More Questions & Answers
Grenoble to Madrid bus services, operated by BlaBlaCar Bus, arrive at Lyon - Gerland Bus Station.
Grenoble to Madrid train services, operated by Société Nationale des Chemins de fer Français (SNCF), arrive at Valence Tgv Rhone-Alpes Sud station.
Yes, the driving distance between Grenoble to Madrid is 1188 km. It takes approximately 11h 33m to drive from Grenoble to Madrid.
Book your Grenoble to Madrid train tickets online with Omio.
Book your Grenoble to Madrid bus tickets online with Omio.
There are 7030+ hotels available in Madrid.




































